青岛地区感染后肠易激综合征的临床特点  

The clinical characteristics of postinfectious irritable bowel syndrome in Qingdao

作　　者：鞠辉[1] 刘希双[1] 王光兰[1] 张海燕[1] 戴素美[1] 毛涛[1] 

机构地区：[1]青岛大学医学院附属医院内镜诊疗科,266003

出　　处：《中华内科杂志》2009年第6期473-475,共3页Chinese Journal of Internal Medicine

摘　　要：目的调查分析青岛地区感染后肠易激综合征（PI-IBS）患者的临床特点。方法收集门诊IBS患者，采用问卷调查方式，内容包括一般资料、症状和微生态制剂治疗前后的生活质量表。结果（1）PI—IBS患者中女性患病率是男性的2．2倍，与非感染后肠易激综合征（non—PI-IBS）相近；（2）PI—IBS与non—PI—IBS患者都以脑力劳动者居多；（3）PI—IBS与non—PI—IBS患者的消化系统以外的伴随症状中，以躯体性不适为主的表现（疲劳、头痛、头晕、背痛等）的差异无统计学意义（Х^2=10．5，P〉0．05），而以精神性不适为主的表现（紧张、多疑、抑郁、焦虑等）PI—IBS要明显多于non-PI—IBS，差异有统计学意义（Х^2=28．7，P〈0．05）；（4）PI-IBS的肠道菌群失调率明显高于non-PI—IBS患者；（5）PI-IBS患者在双歧三联活菌治疗1个月后，生活质量评分的差异有统计学意义（t=3．8，P〈0．01），而non—PI—IBS患者治疗前后的差异无统计学意义（t=1．5，P〉0．05）。结论青岛地区PI-IBS与non—PI—IBS的某些临床特点存在差异。Objective To investigate the clinical characteristics of postinfectious irritable bowel syndrome （PI-IBS） in Qingdao. Methods Two hundred and four PI-IBS and 2068 non-PI-IBS patients were investigated with questionnaire including general information, symptoms and quality of life scores with microecological study before and after therapy. Results （ 1 ） The morbidity rate of PI-IBS in female was 2. 2 times of that in male, which was similar to that in non-PI-IBS. （2） Brainwork labors dominated in both PI-IBS and non-PI-IBS patients. （3） As to the simultaneous presence of extra-gastrointestinal symptoms, there was no statistical difference between the rate of physical symptoms in PI-IBS and non-PI-IBS patients （ Х^2 = 10. 5 ,P 〉 0. 05） ,but the rate of mental symptoms was higher in PI-IBS than in non-PI-IBS patients, and the difference was significant（ Х^2 = 28.7, P 〈 0.05 ）. （4）The alteration of intestinal microflora rate in PI-IBS was obviously higher than that in non-PI-IBS patients. （5） The quality of life scores in PI-IBS was improved after treatment with Birid Triple Viable , and there was significant difference（ t =3.8, P 〈 0. 01 ）, but there was no statistical difference in non-PI-IBS （t = 1.5, P 〉 0. 05）. Conclusion There was some difference in certain clinical characteristics between PI-IBS and non-PI-IBS patients in Qingdao.

关 键 词：肠易激综合征 肠道菌群 临床特点 

分 类 号：R686[医药卫生—骨科学]