梗阻性黄疸患者丙泊酚和七氟烷麻醉术后苏醒时间的比较  

Comparison of recovery times from anesthesia with propofol and sevoflurane in obstructive jaundice patients

作　　者：陆智杰[1] 苗青[1] 缪雪蓉[1] 王晓燕[2] 邱海波[1] 俞卫锋[1] 

机构地区：[1]第二军医大学东方肝胆外科医院麻醉科,上海200438 [2]解放军总医院第一附属医院麻醉科

出　　处：《中国现代医药杂志》2009年第5期9-11,共3页Modern Medicine Journal of China

摘　　要：目的比较梗阻性黄疸患者丙泊酚和七氟烷麻醉术后的苏醒时间。方法60例上腹部手术患者,ASAI～II级,按血胆红素分为黄疸组和无黄疸对照组,每组30例。其中黄疸组患者均为梗阻性黄疸,血清总胆红素浓度(TBL)≥171μmol/L。再将对照组和黄疸组分别随机分为丙泊酚组和七氟烷组,每组15例。丙泊酚组为常规麻醉诱导后丙泊酚全凭静脉麻醉,维持BIS值45,术毕即停丙泊酚;七氟烷组为常规麻醉诱导后吸入1%～2%七氟烷,维持BIS值45,术毕即停吸七氟烷。同时记录从停药后至BIS值达到90的时间和唤醒时间。结果七氟烷处理的黄疸组苏醒时间长于丙泊酚处理的黄疸组,有统计学差异。丙泊酚处理的黄疸组与对照组的苏醒时间无显著差异。结论黄疸患者七氟烷麻醉苏醒时间延长,但丙泊酚对黄疸患者的苏醒时间无影响,丙泊酚可能比七氟烷适合黄疸患者麻醉。Objective To observe the recovery times after propofol and sevoflurane anesthesia in obstructive jaundice pa- tients. Methods Sixty patients undergoing abdominal surgery were divided into two groups according to the total bilirubin level in blood： control group without jaundice and jaundice group with 30 cases of each group. Jaundice group are obstructive jaundice patients with TBL ≥171μmol/L.Control group and jaundice group were respectively divided into propofol and sevoflurane with 15 cases of each group.After patients conventional induced of anesthesia, propofol or sevoflurane are used to maintain the BIS value of 45. At the end of the surgery, the time reached BIS90 and wake-up time were recorded. Results The recovery times of patients after sevoflurane anesthesia with obstructive jaundice prolonged significantly compared with patients after propofol anesthesia. However, no differences were observed in propofol group. Conclusion Recovery from anesthesia with sevoflurane is delayed in obstructive jaundice patients, but the recovery times is not delayed in propofol group. Propofol is possibly suit with sevoflurane anesthesia in obstructive jaundice patients.

关 键 词：梗阻性黄疸 丙泊酚 七氟烷 苏醒时间 

分 类 号：R614[医药卫生—麻醉学] R575[医药卫生—外科学]