慢性肝性脑病的磁共振成像及其波谱表现  

MRI and MRS Findings of Chronic Hepatic Encephalopathy

作　　者：张金华[1] 孟宪平[1] 冯东侠[2] 张怡璐[1] 姜岐涛[1] 陆亚萍[1] 

机构地区：[1]东南大学医学院附属江阴医院MRI室,江阴214400 [2]东南大学微侵袭神经外科研究所,江阴214400

出　　处：《中国医学影像学杂志》2009年第3期211-213,共3页Chinese Journal of Medical Imaging

摘　　要：目的:分析慢性肝性脑病的MRI及其波谱特点,探讨其诊断价值。材料和方法:对8例慢性肝性脑病行MRI及1H-MRS STEAM法检查,观察慢性肝性脑病MRI图像表现及波谱图像主要代谢峰Cho、mI、Glx、NAA、Lip/Lac的变化。结果:4例肝性脑病MRI图像出现苍白球及邻近区域对称性短T1等T2信号影,1例出现基底核团对称性长T1长T2信号影,1例同时出现上述两种改变,2例无明显改变。波谱图像上均表现为Cho、mI降低,Glx升高、NAA、Lip/Lac改变不明显。结论:慢性肝性脑病MRI具有表现特点,波谱能准确、较早反映脑内代谢变化。Purpose： To study the features of MRI and MRS of chronic hepatic encephalopathy. Materials and Methods： The signal changes observed on MRI images and Cho,mI,Glx,NAA ,Lip/Lac manifestation on MRS in 8 patients with chronic hepatic encephalopathy. Results： Of 8 patients, 4 appeared signal hyperintense on T1WI and isointense on T2WI in bilateral globuses, 1 appeared hypointense on T1WI and hyperintense on T2WI in bilateral basal nuclei, 1 appeared both above,2 appeared normal signal. All 8 patients appeared decreased mI and Cho, increased Glx, normal NAA and Lip/Lac. Conclusion： Chronic hepatic encephalopathy has its features in images of MRI. MRS can refelect metabolism changes more accurately and early.

关 键 词：肝性脑病 磁共振成像 氢质子波谱 

分 类 号：R445.2[医药卫生—影像医学与核医学]