三七总皂苷分散片的研究  

Research on the Radix Notoginseng Total Saponin Dispersible Tablets

作　　者：常春明[1] 

机构地区：[1]首都医科大学附属北京儿童医院,北京市100045

出　　处：《中国医院用药评价与分析》2009年第4期291-293,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:本实验制备了三七总皂苷分散片,以达到提高药物溶出,改善吸收。方法:采用高效液相色谱法测定我们制备的三七总皂苷分散片和血栓通制剂的溶出度。结果及结论:目前上市的血栓通胶囊30分钟的溶出度不超过50%,制成分散片后10分钟即可达到80%以上,30分钟全部溶出。OBJECTIVE： To prepare Radix Notoginseng total Saponin Dispersible tablets to enhance the dissolution rate and improve its absorbability. METHODS： The dissolution rates of Radix Notoginseng total Saponin Dispersible tablets and Xueshuantong preparation were determined by HPLC. RESULTS ＆ CONCLUSION： The dissolution rate of Xueshuantong capsule available in the market was no more than 50% within 30 minutes, but up to over 80% within 10 minutes and 100% within 30 min after being prepared into dispersible tablets.

关 键 词：三七总皂苷 分散片 溶出度 高效液相色谱法 

分 类 号：R932[医药卫生—生药学]