磁共振扩散加权成像对慢性胰腺炎及胰腺癌的诊断价值分析  

Diagnostic value of Diffusion-weighted Imaging in Chronic Pancreatitis and Pancreatic Cancer

作　　者：章瑜[1] 靳二虎[1] 

机构地区：[1]首都医科大学附属北京友谊医院放射科,北京100050

出　　处：《临床放射学杂志》2009年第5期644-647,共4页Journal of Clinical Radiology

摘　　要：目的探讨3.0T磁共振扩散加权成像(DWI)及表观扩散系数(apparent diffusion coefficient,ADC)对于慢性胰腺炎及胰腺癌的诊断价值。资料与方法对15名健康自愿者、16例慢性胰腺炎和15例胰腺癌患者进行DWI扫描,采用单次激发自旋回波-回波平面成像(SE-EPI)序列,b值为0、600和0、1000s/mm2。测量胰腺ADC值,比较不同b值下,自愿者组、慢性胰腺炎组、胰腺癌组的ADC值差异。结果自愿者组、慢性胰腺炎组、胰腺癌组在b值为0、600s/mm2时,三组的ADC值(10-3mm2/s)95%可信区间分别是3.176～1.670(2.423±0.384)、2.153～1.287(1.720±0.221)、1.613～1.005(1.309±0.155);b值为0、1000s/mm2时,三组的ADC值(10-3mm2/s)95%可信区间分别是2.456～1.390(1.923±0.272)、1.979～1.085(1.532±0.228)、1.585～0.773(1.179±0.207)。三组的ADC值差异在b值为0、600及0、1000s/mm2时,均有统计学意义(P<0.05)。结论测量DWI中胰腺的ADC值对于胰腺癌与慢性胰腺炎的鉴别诊断有一定意义。[ Abstract] Objective To determine the value of diffusion-weighted imaging （DWI） and corresponding apparent diffu- sion coefficient （ADC） in the diagnosis of chronic pancreatitis （CP） and pancreatic cancer（ PC ） at 3.0 T. Materials and Methods Fifteen volunteers, 16 cases of CP and 15 cases of PC were performed DWI scan with single shot SE EPI sequence, and b value （ s/mm^2 ） were 600 and 1000 respectively. The ADC values of normal pancreas, CP and PC were measured and analyzed statistically. Results When b value was 600 s/mm^2, the ADC value （10-3 mm^2/s） of normal pancreas, CP and PC were 3. 176 - 1. 670.（ 2. 423 ± 0. 384 ）, 2. 153 - 1. 287 （ 1. 720 ± 0. 221 ）, 1. 613 - 1. 005 （ 1. 309 ± 0. 155）respectively. When b value was 1000 s/mm^2, the ADC value（ 10-3 mm^2/s） of normal pancreas, CP and PC were 2. 456 - 1. 390 （ 1. 923 ± 0. 272）, 1. 979 - 1. 085 （ 1. 532 ± 0. 228 ）, 1. 585-0.773 （ 1.179 ± 0.207 ）. There was statistically significant difference among normal pancreas group, CP group and PC group when b value was 600 and 1000 s/mm^2 （P 〈 0.05） . Conclusion ADC values were helpful in the differential diagnosis of PC and CP.

关 键 词：胰腺炎 慢性 胰腺肿瘤 磁共振成像 扩散加权成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R576[医药卫生—诊断学] R735.9[医药卫生—临床医学]