0.375%罗哌卡因与0.375%布比卡因用于乳腺癌手术硬膜外麻醉的比较  

Comparative Study of 0.375% Ropivacaine and 0.375% Bupivacaine Applying in Epidural Anesthesia in Breast Cancer

作　　者：吴方强[1] 赵家旭[1] 王正陆[1] 陈晶[1] 戴宁[1] 

机构地区：[1]黑龙江省医院,黑龙江哈尔滨150036

出　　处：《黑龙江医学》2009年第3期220-221,共2页Heilongjiang Medical Journal

摘　　要：目的比较0.375%罗哌卡因与0.375%布比卡因应用于乳腺癌手术时硬膜外麻醉的效果。方法选择60例ASAⅠ～Ⅱ级择期乳腺癌手术病人,排除心、肝、肾等主要脏器功能障碍的病例。采取随机双盲法,将60例病人分为两组,即0.375%罗哌卡因组（Ⅰ组）和0.375%布比卡因组（Ⅱ组）,常规监测ECC、BP、SPO2,采用100 mm长的VAS标尺,在切皮、清扫腋窝淋巴结以及手术缝皮时记录病人自己对疼痛的评分,注意循环的变化,记录不良反应。结果两组在术中各主要操作点VAS平均评分无显著性差异。结论在乳腺癌手术硬膜外麻醉时选用0.375%罗哌卡因安全有效,鉴于对血压波动可减少对运动神经阻滞程度的特点,值得临床应用。ObjectiveTo compare the effect of 0.375 % ropivacaine and 0. 375 % bupivacaine applying in epidural anesthesia in breast cancer. Methods60 cases of such patients （ASA Ⅰ - Ⅱ grade, no principal organ dysfunction） were divided into ropivacaine group（ Ⅰ group） and bupivacaine group （ Ⅱ group） using random double- blind method. ECC, BP, SPO2, painful score, circular changes and adverse effec were recorded. Results There were no significant difference in VAS score of main record point. Conclusion It is safe and effective to choose ropivacaine during epidural anesthesia in breast cancer and worth to applied in clinic.

关 键 词：乳腺癌 罗哌卡因 布比卡因 

分 类 号：R614[医药卫生—麻醉学]