舒芬太尼及芬太尼对患者气管插管心血管反应抑制效应的比较  

The Cardiovascular Suppressing Effect of Sulfentanyl and Fentanyl in Tracheal Intubation Patients

作　　者：杨春友[1] 苏凤荣[1] 

机构地区：[1]哈尔滨医科大学第五临床医学院,黑龙江大庆163316

出　　处：《黑龙江医学》2009年第5期374-376,共3页Heilongjiang Medical Journal

摘　　要：目的比较等效镇痛剂量舒芬太尼及芬太尼对全麻诱导气管插管时心血管反应的抑制效应,为临床应用提供参考。方法选择择期手术给予全身麻醉患者68例。ASAⅠ级或Ⅱ级。年龄18～64岁。体重42～68kg。肝、肾和心血管功能未见异常,无药物成瘾史,无内分泌疾病史,无明显插管困难体征(Wilson综合评分<3分)。随机分为2组(n=34):舒芬太尼组(S组)及芬太尼组(F组)。采用SPSS11.0软件分析数据,计量资料以均数±标准差(x-±s)表示,组内比较采用重复测量数据的方差分析,组间比较采用成组t检验,计数资料比较采用χ2检验,P<0.05为差异有统计学意义。结果与等效剂量的芬太尼相比,舒芬太尼可更有效地减轻全麻诱导气管插管时患者的心血管反应。Objective To compare the cardiovascular suppressing effect of equivalent dose Sulfentanyl and Fentanyl in general anesthesia induced tracheal intubation. Methods 68 cases of general anesthesia patients , grade Ⅰ or Ⅱ of ASA, age 18 - 64, body weight 42 to 68 Kg, no liver, kidney and cardiovascular system disfunction, no drug addiction history, no endocrine system diseases history, no obviously difficult eannula sign（Wilson score 〈 3） were investigate and were divided into tow groups（ n = 34） ： Sulfentanyl group（s group） and Fentanyl group. The data is analyzed by SPSS 11.0 soft. Results Sulfentanyl could more effect abatement cardiovascular effects of general anesthesia induced tracheal intubation patients than equivalent dose fentanyl.

关 键 词：舒芬太尼 芬太尼 等效剂量 

分 类 号：R614[医药卫生—麻醉学]