双水平正压无创机械通气治疗慢性阻塞性肺病合并呼吸衰竭的应用研究  

作　　者：贾坤林[1] 徐翠蓉[1] 

机构地区：[1]四川省简阳市人民医院呼吸内科,641400

出　　处：《当代医学》2009年第15期4-5,共2页Contemporary Medicine

摘　　要：目的探讨双水平正压无创机械通气治疗慢性阻塞性肺病合并呼吸衰竭的临床效果。方法将60例慢性阻塞性肺病合并Ⅱ型呼吸衰竭患者随机平行分为治疗组和对照组各30例。对照组给予抗感染、支气管扩张剂、止咳化痰、雾化吸入及支持治疗,治疗组在以上治疗的基础上给予无创机械通气模式。结果双水平正压无创机械通气对提高PaO2和降低PaCO2效果好,治疗组与对照组比较差异有统计学意义(P<0.05),治疗组患者平均住院时间缩短,血气改善时间提前,血气改善程度更好,无腹胀、皮肤压伤或呼吸机相关肺炎发生。结论双水平正压无创机械通气对慢性阻塞性肺病合并Ⅱ型呼吸衰竭的治疗效果好,安全有效,减少患者痛苦,降低住院费用。Objective To evaluate the clinical efficacy of BiPAP non-invasive mechanical ventilation in the treatment of COPD patients with respiratory failure. Methods 60 patients with COPD with type II respiratory failure were devided into the intervention group（30cases） and control group（30 cases）.The control group was given antiinfection, eliminating phlegm, relieving asthma, hormone and supply treatment, the intervention group were treated with BiPAP ventilation in addition to above routine treatment. Results PaO2 and PaCO2 changed significantly more in the intervention group than that in the control group （P〈0.05）, mean hospital time shortened, the time of blood gas improvement brought forward and bettered, no abdominal distention, skin crush and ventilator-associated pneumonia was complicated. Conclusion BiPAP non-invasive mechanical ventilation as an auxiliary treatment is definitely valuable for COPD patients with type-Ⅱ respiratory failure, efficient and safe, Reduced hospitalization costs.

关 键 词：双水平正压通气 无创机械通气 慢性阻塞性肺病 呼吸衰竭 

分 类 号：R563.9[医药卫生—呼吸系统] R563.8[医药卫生—内科学]