乙型肝炎患者血清β_2-微球蛋白107例的临床观察  

作　　者：赖志伟[1] 

机构地区：[1]广东清远市人民医院,511500

出　　处：《当代医学》2009年第15期77-78,共2页Contemporary Medicine

摘　　要：目的探讨乙型肝炎血清β2微球蛋白(β2-MG)水平与肝组织损伤程度之间的关系。方法应用放射免疫法(RIA)检测42例重度、65例中轻度慢性乙型肝炎患者及33例正常人血清β2-MG水平。结果重度慢性乙型肝炎血清β2-MG水平显著高于中、轻度乙型肝炎及正常人血清β2-MG水平;慢性乙型肝炎血清β2-MG水平与血清白蛋白呈负相关(P<0.05),与丙氨酸转氨酶、总胆红素、凝血酶原活动度呈正相关(P<0.05)。结论血清β2-MG水平是反映肝组织损害程度良好的指标,对了解肝炎病情危重程度、判断预后有重要意义。Objective To study the relationship between the level of serum β2-microglobulin and the degree of liver damage in patients with hepatitis B. Methods Using radiation immune assay （RIA） to detect of serum β2-microglobulin in 42 patients with grave hepatitis, 65 patients with chronic hepatitis B and 33 contrasts. Results The level of serum β2-microglobulin in patients with grave hepatitis is significantly higher than that in patients with chronic hepatitis B and contrasts, it also showed negative correlation with Alb, positive correlation with ALT, T-Bil and PTA in patients with grave hepatitis. Conclusion Serum β2-MG is a good index that reflects the degree of liver damage, and is important in realizing the state and prognosis of the patients with grave hepatitis B.

关 键 词：乙型肝炎 患者 血清Β2-微球蛋白 临床 

分 类 号：R512.6[医药卫生—内科学] R817.4[医药卫生—临床医学]