重型肝病原位肝移植术后肺部感染的防治  

The strategy of prevention and treatment of pulmonary infection after orthotopic liver transplantation of fulminant hepatitis

作　　者：曲明 王营 史艳芬 杜英东 尹惠生 夏强[2] 张建军[2] 陈小松[2] 

机构地区：[1]107医院肝胆外科,山东烟台264002 [2]上海仁济医院肝脏移植中心,上海200001

出　　处：《实用医药杂志》2009年第5期3-5,共3页Practical Journal of Medicine & Pharmacy

摘　　要：目的探讨原位肝移植(OLT)术后肺部感染的原因及预防、治疗方法。方法分析2003-03～2007-06在107医院及上海仁济医院接受OLT治疗的65例重型肝病患者中35例肺部感染患者的临床资料,探讨OLT术后肺部感染的原因及预防、治疗方法。结果痊愈28例,病死7例。病原菌分析:痰培养有细菌、真菌阳性结果者32例,其中革兰阴性杆菌占57.3%,革兰阳性球菌占28.5%,真菌感染占14.2%,巨细胞病毒感染3例。结论早期明确OLT术后肺部感染的原因并及时采取有效的预防和治疗措施,是OLT术后肺部感染防治的关键。Objective To explore the causes and strategy of prevention and treatment of pulmonary infections after orthotopic liver transplantation （OLT）. Method The clinical data of 35 patients with pulmonary infections which were from 65 patients with fulminant hepatitis undergoing OLT in No. 107 hospital and Shanghai Ren Ji hospital from March 2003 to June 2007 were analyzed. Result In the 35 patients, 28 recovered, 7died. The sputum culture of 32 cases showed positive for bacteria and fungus, including： Gram-negative bacteria （57.3%）, Gram-positive bacteria （28.5%） and fungus （14.2%）; Cytomegalovirus 3cases. Conclusion Defining the causes of pulmonary infections early and making effective strategy of prevention and treatment are the keys for the prevention and treatment of pulmonary infections after OLT.

关 键 词：原位肝脏移植 肺部感染 防治 

分 类 号：R657.3[医药卫生—外科学]