基于Willgerodt-Kindler反应的两种二茂铁羧酸的合成及机理研究  

Synthesis of Two Ferrocene Carboxylic Acids via Willgerodt-Kindler Reaction and Mechanism

作　　者：邱潇[1] 张久峰[1] 赵红莉[1] 蓝闽波[1,2] 

机构地区：[1]华东理工大学结构可控先进功能材料及其制备教育部重点实验室,上海200237 [2]华东理工大学分析测试中心,上海200237

出　　处：《有机化学》2009年第5期748-752,共5页Chinese Journal of Organic Chemistry

基　　金：NovelandImprovedNanomaterials;ChemistriesandApparatusforNanobiotechnology(NACBO)欧盟第六框架项目(No.500804);科技部国际合作项目(No.0424);上海市纳米专项(No.0652nm020)资助项目

摘　　要：以Na2S·9H2O为催化剂,通过Willgerodt-Kindler反应分别合成了二茂铁乙酸和1,1'-二茂铁二乙酸,用IR,1HNMR,MS和元素分析对产物分别进行了结构表征,并利用GC-MS研究了该反应机理,推测反应是由多硫阴离子进攻羰基α碳所引发,同时讨论了影响反应的各种因素.Ferrocenylacetic acid and 1,1′-ferrocenyldiacetic acid were synthesized via Willgerodt-Kindler reaction in the presence of Na2S·9H2O as catalyst. Their structures were characterized by IR, ^1H NMR, MS techniques and elemental analysis. By GC-MS, the mechanism was proposed that the reaction was initiated by the polysulfide anion attacking at the α-carbon. Further factors affecting the reaction were also discussed.

关 键 词：二茂铁乙酸 1 1′-二茂铁二乙酸 Willgerodt-Kindler反应 合成 机理 

分 类 号：O627.8[理学—有机化学]