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作 者:夏璐[1] 戴欣[1] 袁勤[2] 叶廷军[2] 刘慧黎[1] 诸琦[1] 袁耀宗[1]
机构地区:[1]上海交通大学医学院附属瑞金医院消化科,200025 [2]上海交通大学医学院附属瑞金医院检验科,200025
出 处:《中华消化杂志》2009年第5期296-299,共4页Chinese Journal of Digestion
摘 要:目的探讨超声内镜引导下的细针穿刺检查(EUS-FNA)在消化系占位性病变诊断中的价值。方法2007年5月2008年12月对68例患者行超声内镜检查及超声内镜引导下的细针穿刺检查,对比细胞学和(或)病理学检查结果与术后病理结果及随访结果。结果EUSFNA细胞取材成功率91.18%(62/68)。其中病灶位于食管4例(6.45%,4/62),胃19例(30.65%,19/62),直肠19例(30.65%,19/62),肝脏3例(4.84%,3/62),纵隔4例(6.45%,4/62),淋巴结13例(20.97%,13/62)。40例患者细胞学检查结果阳性,阳性率为64.52%(40/62)。22例患者获得组织碎片或细条行病理学检查,组织获得率为35.48%(22/62),其中10例病理学检查结果阳性,阳性率为45.45%(10/22)。与术后病理结果及长期随访结果对照,EUS-FNA对消化系占位性病变诊断的准确率为85.48%,敏感度为90.91%,特异度为100.00%,阴性预测值为57.14%,阳性预测值为100.00%。结论在消化系占位性病变诊断中,EUS-FNA是一项安全、有效、准确的诊断及鉴别诊断方法,在细胞学诊断中具有重要临床价值。Objective To assess the role of endoscopic ultrasound guided fine needle aspiration (EUS-FNA) for diagnosis of gastrointestinal tract lesions. Methods Sixty-eight patients underwent endoscopic ultrasonagraphy and EUS-FNA between May 2007 and Dec. 2008. The result of cytology and/or pathology was compared with that of surgical finding and follow-up study. Results EUS-FNA was successfully performed on 62 patients with lesions in oesophagus (4 cases), stomach (19 case), rectum (19 cases), liver (3 case), mediastinum (4 cases) and lymph node (13 cases), and had a successful rate of 91.18% (62/68). Among them, the lesions in 40 patients (64.52%) were cytologically confirmed. The lesions in 10 out of 22 patients (35. 48%) were pathologically confirmed. Compared with the results of pathology and long-term followe-up study, the sensitivity, specificity and positive predictive value of EUS- FNA in diagnosis of lesions in gastrointestinal tract was 85. 48%, 100.00% and 90.91%, respectively. The positive predictive value and negative predictive value was 100.00 % and 57.14 %, respectively. Conclusion EUS-FNA is a safe, effective and accurate method for diagnosis of lesions in gastrointestinal tract, and has an important role in cytological diagnosis.
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