不同工艺清热暗疮片治疗家兔耳痤疮的比较研究  

Comparative Study on Therapeutic Effect of Qingre Anchuang Tablets Processed by New or Old Technology on Rabbit Ear Acne

作　　者：陈玉兴[1] 黄雪君[1] 曾晓会[1] 赵自明[1] 杜铁良[1] 

机构地区：[1]广东省中医研究所,广州510095

出　　处：《中药新药与临床药理》2009年第3期215-217,共3页Traditional Chinese Drug Research and Clinical Pharmacology

摘　　要：目的对比应用新、旧两种工艺制备的清热暗疮片对家兔实验性耳痤疮的治疗作用。方法采用煤焦油诱发家兔实验性耳痤疮,观察分别应用新、旧工艺清热暗疮片后,家兔痤疮耳厚度、重量、PGE2含量和组织病理学的变化情况。结果新工艺清热暗疮片能明显降低家兔实验性痤疮耳的厚度,减轻痤疮耳的重量,降低PGE2的含量,并明显减轻痤疮耳的病理改变,相同剂量的新、旧工艺清热暗疮片中,新工艺清热暗疮片作用明显优于旧工艺清热暗疮片。结论新工艺清热暗疮片比旧工艺清热暗疮片对家兔实验性耳痤疮的改善作用更明显。Objective To compare the therapeutic effect of Qingre Anchuang Tablets （QAT） processed by new or old technology on rabbit ear acne. Methods Experimental rabbit ear aene was induced by coal tar. After the modeling, the rabbits were administrated with QAT processed by new or old technology. The thickness, weight and PGE2 level of the acne ear were measured, and the pathological changes of the acne ear were also examined. Results QAT processed by new or old technology could decrease the thickness, weight and PGE2 level of the ear significantly, and relieve the pathological changes of the acne ear. The effects of QAT processed by new technology was better than that of QAT processed by old technology. Conclusion QAT processed by new technology has a better therapeutic effect on rabbit ear aene than QAT processed by old technology.

关 键 词：清热暗疮片 新工艺 痤疮 家兔 

分 类 号：R285.5[医药卫生—中药学]