阴道超声介入治疗输卵管妊娠的临床观察  

Clinical observation on therapeutic effect of transvaginal ultrasound interventional treatment for ectopic pregnancy

作　　者：王东[1] 朱任坚[1] 史纪芳[1] 

机构地区：[1]大理学院附属医院妇产科,云南大理671000

出　　处：《现代医药卫生》2009年第12期1763-1764,共2页Journal of Modern Medicine & Health

摘　　要：目的:探讨阴道超声介入治疗输卵管妊娠的疗效与安全性。方法:将我院确诊为输卵管妊娠的69例患者随机分为两组,对照组(肌内注射MTX)33例,试验组(阴道超声介入下经阴道侧穹窿孕囊内注射MTX)36例。结果:对照组治愈率69.70%,试验组治愈率91.67%。对照组血β-HCG下降至正常所需时间较试验组长,两组比较差异有显著性(P<0.01);试验组治疗1周后B超提示包块明显缩小与对照组比较差异有显著性(P<0.05);试验组住院天数明显少于对照组,两组比较差异有高度显著性(P<0.01);试验组不良反应发生率(白细胞减少、消化道反应)较对照组低,两组比较差异有显著性(P<0.05)。结论:在阴道超声介入下经阴道侧穹窿孕囊内注射MTX较肌内注射MTX治疗输卵管妊娠疗效更显著。Objective：To evaluate the efficacy and safety of transvaginal ultrasound interventional treatment for ectopic pregnancy. Methods：69 patients with ectopie pregnancy were randomly divided into two groups：33 cases in the control group （intramuscular injection of MTX） and 36 cases in the test group （intra-gestational sac injection of MTX via lateral vaginal fomix by transvaginal ultrasound intervention）. Results：The cure rate in the control group and the test group was 69.70% and 91.67% respectively, with statistical difference（P〈0.05）. The time of β-HCG dropped to normal level in the control group was longer than that in the test group （P〈0.01）. The mass manifested by B-mode imaging after 1 week of treatment in the test group reduced obviously compared with the control group （P〈0.01）. The hospitalization days in the test group were shorter than that of the control group with significant difference（P〈0.01）.The test group had signitlcanfly lower adverse reaction rate（WBC decrease, gastrointestinal reactions） compared with the control group（P〈0.05）. Conclusion： The treatment efficacy of intra-gestational sac injection of MTX via lateral vaginal fornix by transvaginal ultrasound interventional excels intramuscular injection of MTX for ectopic pregnancy.

关 键 词：阴道超声介入 异位妊娠 甲基黄嘌呤 

分 类 号：R71[医药卫生—妇产科学]