撞击与注射静脉血建立家兔菜花耳模型的比较研究  

Comparative study of production cauliflower ear in rabbits by striking and injecting venous blood

作　　者：韦文朗[1] 柳大烈[1] 张锡流[2] 刘泳铖[2] 林辉[2] 韦俊彬[2] 

机构地区：[1]南方医科大学附属珠江医院整形外科,广东广州510282 [2]广西中医学院第一附属医院,广西南宁530023

出　　处：《中国美容医学》2009年第5期667-671,共5页Chinese Journal of Aesthetic Medicine

摘　　要：目的:建立家兔菜花耳模型,比较撞击与注射静脉血两种方法的效果。方法:12只家兔分A、B、C三组,每组4只(8只耳廓),A组以重600g、直径4cm的砝码从100cm高落下,撞击到耳廓前外侧面固定的位置上3～7次直至出现明显血肿;B组则往耳廓内注射1ml静脉血,14天重复同样的试验,A、B两组各试验6次,第6次试验后20天结束试验,C组为对照,比较各组试验开始到结束耳廓厚度以及组织病理变化。结果:撞击和注射静脉血均可形成耳廓血肿,多次试验后耳廓增厚,增厚以纤维增生为主,类似人菜花耳的病理变化,反复撞击耳廓比注射静脉血增厚更明显。结论:通过反复撞击家兔耳廓建立菜花耳的动物模型的方法比较理想。Objective To produce cauliflower ear in rabbits and compare which way was better, by striking or injecting blood. Methods 12 rabbits were selected and divided into 3 groups. A 600gm weight was dropped from the height of 100cm onto the lateral surface of the pinna of A group, 3N5 times a day.lml blood was injected into the auricle of B group. The experiment was repeated after 14 days until after the 6th time. C group was blank. The thickness and pathological changing were observed. Results Auricle hematoma was seen after striking or injecting and cauliflower ear appeared while the experiment repeated several times. Most of the thickening part was hyperplastic fibrous tissue like that of cauliflower ear of human. This change was much obvious in A group. Conclusions Repeatedly striking could produce cauliflower ear in rabbits easier.

关 键 词：菜花耳 动物模型 撞击 注射静脉血 

分 类 号：Q813.1[生物学—生物工程]