2007年广东省监狱系统HIV/AIDS患者的CD4^+ T细胞计数结果分析——附436例报告  

Analysis of CD4^+ T lymphocyte counts among prisoners with HIV/AIDS in prison system of Guangdong Province during 2007

作　　者：鄢心革[1] 李杰[1] 刁丽梅[1] 林萍[1] 于国龙[1] 林鹏[1] 

机构地区：[1]广东省疾病预防控制中心,510300

出　　处：《新医学》2009年第6期366-368,共3页Journal of New Medicine

基　　金：广东省医学科学技术研究基金资助项目(2006A077)

摘　　要：目的:了解广东省监狱系统在押HIV/AIDS犯人的细胞免疫状况,为临床防治AIDS提供参考。方法:应用流式细胞仪对436例广东省监狱系统的在押的HIV/AIDS患者进行CD4+T细胞计数,并定期监测。结果与结论:436例中的感染者CD4+T细胞计数结果少于200μ/L者占24.5%,200~350μ/L者占26.6%,超过350μ/L者占48.9%。不同年龄组之间CD4+T细胞计数存在差异,25岁以后随着年龄增长,CD4+T细胞计数呈下降趋势。未经治疗的201例患者3个月后CD4+T细胞计数较首次检测明显下降,而经治疗的20例则明显增加。提示应对HIV/AIDS患者的CD4+T细胞计数进行检测及定期监测,以了解其免疫状态的变化,并应予积极的抗病毒治疗以改善其免疫状况。Objective： To investigate the cell immune status of prisoners with of Guangdong province for offering reference to prevention and treatment HIV/AIDS, analysis were used for CD4^＋ T lymphocyte counts in 436 prisoners with HIV/AIDS in HIV/AIDS in prison system Methods： Flow cytometry prison system of Guangdong province. Results and Conclusion： 24. 5% of 436 HIV positive prisoners had CD4^＋ T lymphocyte counts lower than 200/μL, 26. 6% from 200/μL to 349/p,L, and 48.9% more than 350/p,L. The CD4^＋ T lymphocyte count had significant difference among different age groups, and the CD4^＋T lymphocyte counts in patients over 25 years old trended to decrease with increasing age. Compared to the first test results, the CD4^＋T lymphocyte counts of 201 cases without therapy obviously decreased after 3 months, CD4^＋ T lymphocyte counts of 20 cases with therapy obviously increased inversely. It shows that CD4 ^＋ T lymphocyte counts of HIV/AIDS patients should be detected and followed periodically to comprehend the change of their immune status, and antiviral therapy should be offered energetically to improve their immune status.

关 键 词：人类免疫缺陷病毒 获得性免疫缺陷综合征 监狱 CD4T细胞 抗病毒治疗 

分 类 号：R512.91[医药卫生—内科学]