共聚焦激光扫描显微镜技术在黄褐斑组织分型中的应用  

Application of confocal laser scanning microscopy in histological classification of melasma

作　　者：聂小娟[1] 刘华绪[1] 张福仁[1] 

机构地区：[1]山东省皮肤病性病防治研究所,济南250022

出　　处：《中国麻风皮肤病杂志》2009年第5期321-323,共3页China Journal of Leprosy and Skin Diseases

摘　　要：目的:评价共聚焦激光扫描显微镜(CLSM)技术与组织病理对黄褐斑分型的一致性。方法:应用CLSM对患者皮损进行分层扫描成像并取同处皮损常规组织病理检查,以病理结果为标准对照。结果:CLSM分型结果显示10例患者中7例为表皮型,3例为混合型,其中2例为偏表皮混合型、1例为偏真皮混合型。上述结果与病理分型结果完全吻合。结论:CLSM技术可应用于黄褐斑的组织学分型。Objective： To evaluate the consistency of confocal laser scanning microscopy （CLSM） with histological classification of melasma. Method： The targeted lesion of melasma in each patient was scanned and imaged with CLSM, and then, biopsied for histopathology. The result of CLSM was compared with histopathology. Results： Ten melasma patients were recruited into the study, of whom, 7 were categorized as epidermal type, 3 as mixed including 2 cases being epidermal predominant and 1 case dermal predominant according to CLSM, which was completely consistent with the result of histopathology. Conclusion： CLSM is an alternative method for invasive histopathological examination in the histopathological classification of melasma.

关 键 词：黄褐斑 组织分型 共聚焦激光扫描显微镜 组织病理 

分 类 号：R758.42[医药卫生—皮肤病学与性病学]