超声造影增强形式对乳腺病变的诊断价值  

Usefulness of contrast enhanced ultrasound in the diagnosis of breast lesions

作　　者：刘赫[1] 姜玉新[1] 刘吉斌 朱庆莉[1] 孙强[2] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院超声诊断科,北京100730 [2]中国医学科学院北京协和医学院北京协和医院乳腺外科,北京100730 [3]Department of Radiology, Thomas Jefferson University, Philadelphia, PA, 19107, USA

出　　处：《中华超声影像学杂志》2009年第5期414-417,共4页Chinese Journal of Ultrasonography

基　　金：国家自然科学基金项目（30570529）

摘　　要：目的探讨超声造影在乳腺病变中的应用价值。方法对行乳腺手术的104例患者共104个病灶进行超声造影，将其增强形式分为无增强、周边增强、均匀增强、区域增强和不均匀增强。总结乳腺良、恶性病变的微血管显像特征。结果超声造影无增强提示良性，诊断敏感性18．3％，特异性97．7％，阳性预测值91．7％，阴性预测值46．2％，准确性51．5％。周边增强提示恶性，诊断敏感性39．5％，特异性98．3％，阳性预测值94．4％，阴性预测值69．4％，准确性73．8％。结论超声造影增强形式有助于乳腺病变的鉴别诊断。Objective To evaluate the usefulness of contrast enhanced ultrasound in the diagnosis of breast lesions. Methods Contrast enhanced ultrasound was performed after administration of SonoVue in 104 patients scheduled for surgical tumor removal. The enhancement morphology was classified as non, peripheral ,homogeneous, regional, or heterogeneous enhancement based on distribution of enhancing areas. All breast lesions enhancement morphology were analyzed, and the diagnostic value of contrast enhanced ultrasound was calculated. Results The prevalence of non enhancement was significantly higher in benign lesions than in malignant ones（ P = 0. 013）,and the prevalence of peripheral enhancement was significantly higher in malignant lesions than in benign ones （ P = 6.02 ×10^-7 ）. Conclusions Contrast enhanced ultrasound is useful in diagnosis of breast lesions.

关 键 词：超声检查 造影剂 乳腺肿瘤 诊断 鉴别 

分 类 号：R686[医药卫生—骨科学]