肝癌伴胆管癌栓的临床病理及预后分析  

Correlation between clinicopathological characteristics and prognosis of hepatocellular carcinoma with bile duct thrombi

作　　者：苏昆仑[1] 吴育连[2] 李晔[1] 徐海滨[1] 王建伟[2] 彭淑牖[2] 

机构地区：[1]杭州市中医院外一科,310006 [2]浙江大学医学院附属第二医院外科,杭州310009

出　　处：《中华肝胆外科杂志》2009年第5期371-373,共3页Chinese Journal of Hepatobiliary Surgery

摘　　要：目的探讨肝癌伴胆管癌栓的临床病例特点对预后的影响。方法回顾性分析了1995—2005年21例肝癌伴胆管癌栓的临床病例特点与预后情况。结果该组HCC伴胆管癌栓病人的1年生存率为66．7％，3年生存率为42．9％，中位生存时间为29．5个月。有无癌栓侵犯胆管壁的两组病例生存率差异无显著意义（P〉0．05），癌栓位置不同生存率无差别（P〉0．05）。结论对于HCC伴胆管癌栓病例，胆管壁受侵犯和胆管内癌栓的位置不影响预后。Objective To evaluate the correlation between clinicopathological characteristics of hepatocellular carcinoma （HCC） with bile duct thrombi （BDT） and the prognosis. Methods The clinical data of 21 patients with HCC and BDT receiving surgical intervention from 1994 to 2004 in our hospital were retrospectively analyzed to determine the clinicopathological characteristics and the prognosis. Result The overall 1-year and 3-year survival rates from the time of operation were 66.7% and 42. 9%, respectively, with a median survival time of 29.5 months. There was no significant difference in the prognosis between patients with or without the invasion of bile duct wall （P〉0.05）. The prognosis was also not different in patients with different locations of the thrombi in the bile duct. （P〉0.05）. Conclusion The invasion of bile duct wall and the location of the thrombus in the bile duct are not significant factors affecting the prognosis of patients with HCC and BDT.

关 键 词：癌 肝细胞 胆管癌栓 切除术 预后 

分 类 号：R686[医药卫生—骨科学]