乳腺病变超声造影微血管显像增强形式:与病理对照观察  

Enhancement pattern of breast lesions in contrast enhanced ultrasound:comparative observation with histopathologic findings

作　　者：刘赫[1] 姜玉新[1] 刘吉斌 朱庆莉[1] 孙强[3] 常晓燕[4] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院超声诊断科,北京100730 [2]托马斯杰弗逊大学放射系 [3]中国医学科学院北京协和医学院北京协和医院乳腺外科,北京100730 [4]中国医学科学院北京协和医学院北京协和医院病理科,北京100730

出　　处：《中国医学影像技术》2009年第5期783-785,共3页Chinese Journal of Medical Imaging Technology

基　　金：国家自然科学基金(30570529)

摘　　要：目的探讨乳腺病变超声造影微血管显像的病理组织学基础。方法对104例患者行超声造影微血管显像,观察乳腺病变的微血管显像增强形式,并与病理结果对照。结果超声造影微血管显像增强区主要是原位癌、浸润癌生长旺盛区、导管内乳头状瘤、腺病的小叶增生明显区、纤维腺瘤的生长活跃区、富含血管的间质;未增强区或增强不明显区主要是纤维组织、黏液变、导管扩张。结论乳腺超声造影微血管显像可以反映病变的病理组织学特征。Objective To observe the varied contrast enhanced ultrasound （CEUS） imaging appearances of breast lesions compared with histopathologic findings. Methods CEUS was performed in 104 patients （aged 19--86 years） after administration of SonoVue, and the enhancement patterns was classified as no enhancement, peripheral enhancement, homogeneous enhancement, regional enhancement or heterogeneous enhancement. All patients＂ histologic slides were reviewed compared with CEUS findings. Results Contrast enhanced area corresponded to invasive cancer, DCIS component, intraductal papiloma, inflammatory cell infiltrate, and hypereellularity. Non enhanced area corresponded to low degree cellularity, desmoplastic stroma, degeneration, fibrosis or necrosis. Conclusion . CEUS findings of breast lesions are correlated with histologic features.

关 键 词：乳腺肿瘤 超声检查 造影剂 微血管显像 病理学 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]