前列腺3D ^1H-MRSI：体线圈与直肠内线圈谱线质量对照  

Three-dimensional ^1H-magnetic resonance spectroscopic imaging of prostate gland： using body coil and endorectal coil

作　　者：李新民[1] 王霄英[1,2] 郭雪梅[1,2] 王鹤[1] 蒋学祥[1,2] 

机构地区：[1]北京大学第一医院医学影像科,北京100034 [2]北京大学前沿交叉学科研究院功能成像研究中心,北京100034

出　　处：《中国医学影像技术》2009年第5期848-852,共5页Chinese Journal of Medical Imaging Technology

基　　金：首都医学发展科研基金(2007-2006)

摘　　要：目的比较前列腺体线圈(BODY)与直肠内线圈(ERC)3D 1H-MRSI的谱线质量,探讨BODY MRS临床应用的可行性。方法40例前列腺疾病患者,最终获得可测量的BODY与ERC MRS数据者30例。在MRS上将前列腺中央腺体和外周带左、右侧分为底部、中部及尖部,共12个兴趣区;对比BODY和ERC MRSI的各区对应体素的信噪比(SNR)、脂峰强度、(Cho+Cre)/Cit比值。结果SNR:前列腺外周带的底部、中部及尖部左、右侧的SNR,BODY与ERC比较差异均有统计学意义(P均<0.05),均为SNRERC>SNRBODY;中央腺体底部左、右侧的SNR,BODY与ERC比较差异有统计学意义(P均<0.05),均为SNRBODY>SNRERC;②脂峰强度:前列腺外周带底部的左、右侧及尖部左侧脂峰强度两种线圈比较差异有统计学意义(P均<0.05),ERC>BODY;前列腺中央腺体底部左、右侧及中部左侧脂峰强度两种线圈比较差异有统计学意义(P均<0.05),均为ERC>BODY;③MRS各区体素(Cho+Cre)/Cit比值差异无统计学意义。结论前列腺BODY3D1H MRS总体谱线质量能够接受,虽然波谱的SNR略低于直肠内线圈,但其谱线受脂峰影响较小。Objective To compare the quality of 3D 1H-MRSI of body coil （BODY） and endorectal coil （ERC） in prostate gland examination, and to discuss the clinical feasibility of BODY MRS. Methods Both BODY and ERC MRS were performed in 40 consecutive patients, and measurable MRS data was obtained in 30 patients. The right and left side of the peripheral and central zone of prostate were divided into bottom, middle and tip regions of interesting （ROI）, respectively. Twelve ROIs were obtained in each case. The following parameters relating of MRS quality were compared, i.e. signal-tonoise ratio （SNR）, lipid peak and ratio of （Cho＋Cre）/Cit. Results （1）The SNR in the peripheral zone of different individu- als using ERC was statistically higher than that of using BODY MRS （P〈0.05）. The SNR in the central gland of bottom using ERC was statistically higher than that of using BODY MRS （P〈0.05）.（2）The Lipid Peak in the peripheral zone of the bottom and the left of tip acquired using ERC was statistically higher than that of using BODY MRS （P〈0.05）. The Lipid Peak in the central zone of the bottom and the left of middle acquired using ERC was statistically higher than that of using BODY MRS （P〈0.05）. （3）The mean ratios of （Cho＋Cre）/Cit in the peripheral zone and central zone of different individuals acquired using both coils were not significantly different （P〉0. 05）. Conclusion The MRS data can be reliably acquired using BODY MRSI, while the SNR and the Lipid Peak of BODY are inferior to those of ERC MRS.

关 键 词：前列腺 磁共振波谱 

分 类 号：R445.2[医药卫生—影像医学与核医学] R697.3[医药卫生—诊断学]