川党参药材质量化学成分多指标综合评价研究  

Multi-index based Comprehensive Evaluation of Chemical Constituents in Codonopsis tangshen Oliv.

作　　者：彭锐[1,2] 吴大章[2] 卫莹芳[2] 马鹏[1] 李隆云[1] 

机构地区：[1]重庆市中药研究院,重庆400065 [2]成都中医药大学,成都610075

出　　处：《世界科学技术-中医药现代化》2009年第2期274-277,共4页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家"十一五"科技支撑计划(2006BAI06A11-9):川党参;川续断规范化种植及关键技术研究;负责人:李隆云;重庆市科委自然科学基金(8924):药用植物栽培环境优选的评价新方法研究;负责人:李隆云

摘　　要：目的:探讨建立川党参药材质量的化学成分多指标评价方法。方法:权重分配按客观赋权法计算。TOPSIS评价川党参多指标的质量。结果:四种赋权方法的评价结果基本一致。结论:多指标综合评价与主成分聚类分析、遗传多样性分析和HPLC指纹图谱分析结果一致,并具有可量化的优点,可用于药材质量多指标评价。Authors discuss in the paper to establish a method for evaluating the quality of Codonopsis tangshen Oliv. based on its chemical constituents. It is suggested to distribute the weight using the objective weight method. The multivari- ate quality of Codonopsis tangshen Oliv. is evaluated using TOPSIS method. The evaluating results are almost unanimous for four different weight determining methods. It is believed that the evaluating result of multi-index based comprehensive evaluation is quantifiable, and it is also true to the Principal component analysis of chemical constituents, genetic diversity analysis, and HPLC fingerprint analysis. It is feasible to asses the quality of the medicinal materials using the method.

关 键 词：川党参 化学成分 多指标质量 TOPSIS法 

分 类 号：R14[医药卫生—公共卫生与预防医学] R282