磁共振评价中西医结合治疗强直性脊柱炎的疗效  

Therapeutic effect of combined treatment of traditional Chinese medicine and western medicine for ankylosing spondylitis:MRI evaluation

作　　者：叶素贞[1] 陈德基[1] 黄成辉[1] 李汉文[1] 郭艺[1] 

机构地区：[1]广州医学院第二附属医院放射科,广东广州510260

出　　处：《中国介入影像与治疗学》2009年第3期257-260,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金：2007年广州市中医药中西医结合科技项目(2007B28)

摘　　要：目的观察MRI评价中西医结合治疗强直性脊柱炎疗效价值。方法临床确诊强直性脊柱炎患者60例进入研究,随机平均分为中西医结合治疗组、西医治疗对照组,前者给予补肾强督汤+西医常规治疗,后者给予常规西医治疗。治疗前、后均进行磁共振平扫+增强检查及X线检查,对比治疗前后临床症状、MRI及X线影像改变。结果中西医治疗组有效率为96.67%,西医治疗对照组有效率为73.33%(P<0.05)。治疗后MRI显示关节周围强化程度减弱、软骨侵蚀无增加、骨髓水肿减轻或消失、关节积液减少、异常脂肪沉积减少。治疗前后的强直性脊柱炎患者X线检查对比无明显变化。结论MRI能有效评价强直性脊柱炎治疗效果。Objective To evaluate therapeutic effect of combined treatment of traditional Chinese medicine and western medicine for ankylosing spondylitis （AS） with MRI. Methods Sixty patients diagnosed as AS were divided into 2 groups, i.e. combined treatment of traditional Chinese medicine and western medicine （combination group, 30 patients） and single western medicine group （control group, 30 patients）. All patients underwent MRI and X-ray examination before and after treatment. Results The effective rate of combination group and control was 96. 67% and 73.33%, respectively（P〈 0.05）. Post-therapy MRI showed reduced peri joint enhancement, unchanged cartilage involvement, reduced or disap- peared joint and decreased abnormal fatty deposition. There was no obvious changes on X-ray examination before and after treatment. Conclusion Combined treatment of traditional Chinese medicine and western medicine is a better choice for AS than western medicine single therapy. MRI is a favorable tool of therapeutic effect evaluation.

关 键 词：强直性脊柱炎 中西医结合治疗 磁共振成像 

分 类 号：R593.23[医药卫生—内科学]