中西医结合治疗类风湿关节炎活动期的安全性观察  

A clinical research of safety on treatment of active rheumatoid arthritis with integrated traditional and westen medicine

作　　者：盛正和[1] 刘毅斌[1] 黄艳霞[1] 陈柳芳[1] 刘溯章[1] 赵志雄[1] 陈大宇[1] 

机构地区：[1]广西医科大学第五附属医院,广西柳州545001

出　　处：《中国民族民间医药》2009年第9期40-41,共2页Chinese Journal of Ethnomedicine and Ethnopharmacy

摘　　要：目的:研究祛风除湿、活血养阴中药治疗类风湿关节炎活动期的安全性影响。方法:90例活动期类风湿关节炎病例按性别、年龄、病程均衡后分为基础治疗组、激素组及中药组各30例,分别采用非类固醇抗炎药+改变病情药、小剂量泼尼松+非类固醇抗炎药+改变病情药、中药+非类固醇抗炎药+改变病情药疗8周,评价各组安全性。结果:不良反应的累计积分3组中药组(4.33±2.41)<基础治疗组(8.97±5.12)<激素组(12.67±7.19),3组组间比较差异有统计学意义(P<0.05),结论:中西医结合治疗类风湿关节炎活动期具有更好的安全性。To study the safety of expel wind-evil and remove wetness, promoting blood flow, invigorating yin Chinese herb in treating active rheumatoid arthritis （RA） . Methods 90 patients with active rheumatoid arthritis were randomly allocated to 3 groups： Single NSAID, DMARD×8 weeks （Basic treatment group） , prednisone in combination with NSAID, DMARD×8 weeks （GC group） or Chinese herb in combination with NSAID, DMARDsx8 weeks （Chinese herb group） . Adverse effects of every group were analyzed respectively. Result Adverse effects score was significantly different among the 3 groups. Conclusions Treatment of active rheumatoid arthritis with integrated traditional and westen medicine was the safest among the 3 groups.

关 键 词：关节炎 类风湿 中药 安全性 

分 类 号：R593.22[医药卫生—内科学]