聚焦超声用于轻度宫颈上皮内瘤变治疗的临床研究  

Clinical Study on Mild Cervical Intraepithelia Neoplasia Treated with Focused Ultrasound

作　　者：周小飞[1] 付蓉花[1] 向爱清[1] 金寒莹[1] 陶春霞[1] 闾锦秀[1] 

机构地区：[1]江西省妇幼保健院产科,南昌330006

出　　处：《实用临床医学（江西）》2009年第3期72-74,共3页Practical Clinical Medicine

摘　　要：目的探讨聚焦超声对轻度宫颈上皮内瘤变(CINⅠ)治疗的有效性及安全性。方法将宫颈刮片细胞学检查阳性和(或)阴道镜下取活体组织病检,病理诊断为CINⅠ的患者240例随机分为2组。激光治疗组120例,采用传统的激光烧灼治疗;聚焦超声组120例,采用CZF-1型超声波妇科治疗仪治疗。比较2组的治愈率、残留率、治疗时间及术中、术后并发症的发生情况。结果聚焦超声组的治愈率、病灶残留率分别为95.8%和4.2%,激光治疗组分别为93.3%和6.7%,2组比较差异均无统计学意义(均P>0.05);但前者的一次性治愈率(93.3%)显著高于后者(87.5%),P<0.01。聚焦超声组治疗时间、术后阴道排液及脱痂出血量均低于激光组(P<0.01)。结论治疗剂量的聚焦超声波能安全有效的治疗CINⅠ,且术中、术后并发症少,患者依从性好。Objective To investigate clinical efficacy and safety of focused ultrasound treatment for the mild cervical intraepithelia neoplasia（CIN Ⅰ ）. Methods Two hundred and forty patients with CIN Ⅰ diagnosed through pathology were randomized into two groups. One hundred twenty patients in focused ultrasond group were treated with CZF-1 type ultrasound obstetric therapeuti- cal instrument and one hundred twenty in control group were treated with carbon-dioxide laser. Clinical result, side reaction and complications were compared in two groups. Results In focused ultrasound group,healing rate and residual lesions rate were 95.8% and 4.2% respectively. Compared with control group were 93.3% and 6.7% ,respectively, the differences were insignificant （P〉0.05）;but one-shot healing rate （93.3%） in focused ultrasound group was higher significantly than that （87.5 % ） of contral group （P 〈 0. 01 ）, otherwise, average operation time, vaginal discharge and colporrharge etc in focused ultrasound group were significantly lower than that in control group（P〈0.01）. Conclusion Focused ultrasound could cure CIN Ⅰ availably with less side reaction.

关 键 词：聚焦超声 宫颈上皮内瘤变 轻度 物理疗法 随访 

分 类 号：R71[医药卫生—妇产科学]