脑损伤患者凝血功能水平和预后的相关性探讨  

A Study on the Correlation between Traumatic Coagulopathy and Traumatic Brain Injury

作　　者：樊炜 辛泉[2] 

机构地区：[1]简阳人民医院脑外科,四川简阳641400 [2]成都市第二人民医院脑外科,四川成都610072

出　　处：《华西医学》2009年第4期809-811,共3页West China Medical Journal

摘　　要：目的:探讨脑损伤患者凝血功能水平与颅脑损伤伤情转归的相关性。方法:收集70例颅脑损伤患者的临床资料,伤者抽取静脉血2 mL,进行凝血功能检测,分析结果与临床资料等分别采用SPSS 11.5软件进行χ2检验和logistic回归分析。结果:在13例凝血功能异常患者中有5例(38%)伤情加重(较入院时脑内血肿体积增大,迟发性血肿等),明显高于凝血功能正常而伤情加重者(12%,P<0.05);单因素和多因素logistic回归分析提示凝血功能异常时脑损伤伤情加重的危险因素。结论:脑创伤后凝血功能异常时颅脑损伤患者伤情加重的危险因素。Objective： To determine the relationship between traumatic coajulopathy and the patient＇s condition after traumatic brain injury. Methods： Venous blood was collected at the time of admission to detect the coagulability. X^2 test and logistic regression analyses via SPSS version 11.5 were performed to analyze the coajulability and clinical date. Results： In 70 patients, 5 （38%） of 13 patients with abnormal coagulability had a deteriorated condition, which was significantly different from 7 （12%） of 57 patients whose coagulability was normal （P〈0.05）. Logistic regression analyses showed that traumatic coagulopathy was a risk factor to injury aggravation after traumatic brain injury. Conclusion： Traumatic coagulopathy was a risk factor to injury aggravation after traumatic brain injury.

关 键 词：脑损伤 凝血功能 相关性 

分 类 号：R651.15[医药卫生—外科学] R446.11[医药卫生—临床医学]