新生儿铜绿假单胞菌肺炎临床分析  

Study on Newborn Pneumonia of Pseudomonas Aeruginosa

作　　者：罗玉蓉[1] 张砺[1] 

机构地区：[1]成都市儿童医院,四川成都610017

出　　处：《华西医学》2009年第5期1154-1155,共2页West China Medical Journal

摘　　要：目的:探讨新生儿铜绿假单胞菌肺炎的临床特点及药敏特点,为合理治疗提供依据。方法:对我院新生儿科2006年8月到2008年7月收治新生儿肺炎痰标本进行培养分离鉴定,选择培养结果为铜绿假单胞菌者做药敏及临床分析。结果:铜绿假单胞菌对碳青霉烯类,如:亚胺培南,美洛培南敏感率达100%,对近几年在新生儿较少用的或不用的氨基糖甙类,环丙沙星敏感率为85%～100%,而对常用的氨苄西林+舒巴坦不敏感,对头孢他啶敏感率>70%,临床根据药敏结果选择敏感抗生素治疗,疗效满意。结论:近年新生儿铜绿假单胞菌肺炎有上升趋势,病死率极高,故应根据药敏试验结果选择敏感抗生素,以控制疾病发展,降低病死率。Objective： To investigate clinical trait and the drug sensitivity about newborn pneumonia of Pseudomonas aeruginosa and provide the evidence of reasonable treatment. Methods：After cultivating, separating and identifying the sputum samples, from the patients who were diagnosed as newborn pneumonia in newborn department of our hospital from 2006. 8 to 2008. 7, only the patients whose culture results were Pseudomonas aeruginosa were chosen to do the drug sensitivity tests and clinical analysis. Results： Pseudomonas aeruginosa was 100% sensitive to carbopenems, e. g imipenem and mero- penen, and 85% - 100% to amino glycosides and ciprofloxaein, which were hardly used in newborn in recent years. While it was resistant to commonly used ampicillin-sulbactam, and above 70% was sensitive to ceftazidime. The selection of sensitive antibiotics according to results of drug sensitivity test can gain satisfactory treatment outcomes in clinic. Conclusion： Recently newborn pneumonia of Pseudomonas aeruginosa was increasing and the case-fatality was very high. So in order to control the development of diseases and cut down the case-fatality rate, the selection of sensitive antibiotics should be guided by the result of drug sensitivity tests.

关 键 词：新生儿 肺炎 铜绿假单胞菌 

分 类 号：R722.1[医药卫生—儿科]