冠状动脉内超声成像对斑块形态、临床综合征及冠状动脉造影的对比研究  

Intracoronary ultrasound imaging correlation of plaque morphology with clinical syndrome and angiography

作　　者：曾勇[1] 朱文玲[1] 黄超联[1] 张德利[1] 金征宇[1] 沈珠军[1] 倪超[1] 姜秀春[1] 

机构地区：[1]中国医学科学院中国协和医科大学北京协和医院

出　　处：《中华心血管病杂志》1998年第3期190-192,共3页Chinese Journal of Cardiology

摘　　要：目的研究血管内超声对冠状动脉内斑块形态的分析，以及斑块形态与患者临床表现的关系。方法对４２例冠心病患者行冠状动脉造影及冠状动脉内超声成像检查（ＩＣＵＳ），定性分析斑块形态和性质，并与冠状动脉造影对比。患者根据临床特征分为不稳定型心绞痛组（Ａ组）和稳定型心绞痛组（Ｂ组）。结果冠状动脉造影发现，冠状动脉狭窄程度两组比较无显著性差异，而对比两组超声斑块形态和性质发现Ａ组病变以软斑块多见（Ａ组６６％，Ｂ组３１％，Ｐ＜０．０５），Ｂ组则以纤维斑块更常见（Ｂ组５４％，Ａ组１７％，Ｐ＜０．０５）。结论ＩＣＵＳ对病变形态和性质的分类与临床综合征关系更密切。Objective To establish the relationship between ultrasound derived atheroma morphology and angiography with clinical syndrome. Methods Forty two patients were examined by intracoronary ultrasound imaging (ICUS) and coronary angiography. Ultrasound images were analyzed for percent plaque areas and classified into four morphologic subtypes (soft, fibrous, calcific, mixed plaque). Ultrasound data were compared with angiographic feature and clinical angina pattern.Results Ultrasound lesion morphology well correlated with the clinical angina syndrome. Compared with stable angina, patients with unstable angina had more soft lesions (66% vs 31%, P <0.05), less fibrous lesions (17% vs 54%, P <0.05). But the degree of stenosis shown angiographically revealed no significant difference between patients of stable and unstable angina. Conclusion ICUS can detect early process of atherosclerosis. Ultrasound classification of plaque morphology is closely correlated with clinical angina sysdrome.

关 键 词：冠心病 心绞痛 ICUS 诊断 冠状动脉造影 

分 类 号：R541.404[医药卫生—心血管疾病]