醛糖还原酶抑制剂的微量筛选模型的建立  

A MICROSCREENING METHOD FOR ALDOSE REDUCTASE INHIBITORS

作　　者：彭剑[1] 顾性初[1] 龚炳永[1] 

机构地区：[1]上海医药工业研究院

出　　处：《中国医药工业杂志》1998年第5期221-223,204,共4页Chinese Journal of Pharmaceuticals

摘　　要：从牛晶状体中提取醛糖还原酶，采用９６孔板建立该酶的体外微量高效筛选模型，筛选过程简便快捷。Aldose reductase was extracted from calf lenses and a high throughput microscreening method was set up in 96 well microplate. This method is convenient and rapid for screening naturalproduct extracts and synthetic compounds for new aldose reductase inhibitors.

关 键 词：醛糖还原酶 酶抑制剂 微量筛选模型 糖尿病 

分 类 号：R977.15[医药卫生—药品] R587.1[医药卫生—药学]