硫酸/丙醇法制备淀粉硫酸钠的工艺研究  

Preparation of Starch Sulphate Using Concentrated Sulfuric Acid and Propanol

作　　者：林建平[1] 吴小立[2] 方磊[1] 林东强[1] 姚善泾[1] 

机构地区：[1]浙江大学化学工程与生物工程学系,浙江杭州310027 [2]宁波港集团有限公司,浙江宁波315800

出　　处：《高校化学工程学报》2009年第3期455-459,共5页Journal of Chemical Engineering of Chinese Universities

基　　金：国家自然科学基金(20776129;20876139)

摘　　要：提出了以浓硫酸和正丙醇的混合溶液为磺化剂、玉米淀粉为原料、低温下磺酸化反应制备淀粉硫酸钠的工艺路线。考察了反应温度、反应时间、液固比、反应液配比等对淀粉硫酸钠取代度和得率的影响,得到优化制备条件为:硫酸/正丙醇的摩尔比为1.8,反应液/淀粉的液固比为30,反应温度-2℃,反应时间16h,淀粉硫酸钠取代度可达0.58。通过调节反应条件,可控制取代度在0.1～0.6之间。所开发的淀粉硫酸钠制备新工艺,比较环保和经济,过程避免使用有毒试剂,产品可用于医药用途。Using the sulfate was prepared mixture of concentrated The effects of some sulfuric acid and n-propanol important factors, such as as sulphonating agent, the starch reaction temperature and time, liquid-to-solid ratio and the ratio of concentrated sulfuric acid to n-propanol in the reactant mixture, on the yield and degree of substitution of the starch sulfate prepared were investigated. The optimized preparation conditions were obtained as follows： the ratio of concentrated sulfuric acid to n-propanol is 1.8, the liquid-to-solid ratio of reactant is 30, reaction temperature and time are -2℃ and 16 h, respectively. Using above preparation conditions, the degree of substitution of the starch sulfate prepared can reach about 0.58; and it can be controlled to be 0.1-0.6 by adjusting the preparation conditions. Since in the new method developed for the preparation of starch sulfate in the present work not any toxic reagent is used, it is an environment-friendly and economic process, and the starch sulfate prepared has a potential application for the medical uses.

关 键 词：淀粉硫酸钠 浓硫酸 正丙醇 取代度 

分 类 号：TQ031.9[化学工程]