精子形态与顶体酶活性关系的研究  

Study of the relationship between sperm morphology and sperm acrosin activity.

作　　者：包华琼 蔡敏 陈可 

机构地区：[1]重庆市人口和计划生育科学技术研究院,400020

出　　处：《中国优生与遗传杂志》2009年第6期99-100,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨精子形态与精子顶体酶活性的关系。方法对395例男性不育患者采用精子形态检测系统下人工修正方法分析精子形态,用酶标法检测精子中的顶体酶和顶体酶活力指数(AAI)。结果精子形态正常组的顶体酶活性明显高于精子形态异常组,两组差异显著(P<0.05);顶体酶活性正常组形态正常精子百分率明显高于顶体酶活性异常组形态正常精子百分率,两组间较差异极显著(P<0.001);顶体酶活性与形态正常精子百分率间呈显著正相关关系(r=0.169,P<0.001)。结论精子形态可影响精子顶体酶活性。Objective： To study the relationship between sperm morphology and acrosin activities. Methods： The sperm morphology were analyzed by automated sperm morphology analyzer （ASMA） and the sperm acrosin activities were determined by elasa. Resuits ： The acrosin activities of abnormal sperm morphology group are lower than that of normal sperm morphology group （ P 〈 0. 05 ）. The normal morphology sperm rate of abnormal acrosin group is lower than that of normal acrosin group （ P 〈 0. 001 ）. There were significantly positive correlation relationship between the acrosin activities and the rate of normal sperm orphology （ r = 0. 169, P 〈 0. 001 ）. Conclusion ： The sperm morphology could affect sperm acrosin activities.

关 键 词：男性不育 精子形态 精子顶体酶 

分 类 号：R698.2[医药卫生—泌尿科学]