可逆性左室功能紊乱  

Transient left ventricular dysfunction

作　　者：张利环(综述)[1] 杜凤和(审校)[1] 

机构地区：[1]首都医科大学附属北京天坛医院心血管内科,北京100050

出　　处：《中国急救医学》2009年第6期556-558,共3页Chinese Journal of Critical Care Medicine

基　　金：国家自然基金资助项目（No.C03030201）

摘　　要：日本学者首次提出了Tako-tsubo综合征（心尖球样综合征），自此之后，此种综合征日益受到人们的广泛重视。此病常发生于情感打击或应激情况下的老年女性，临床特点主要包括急性缺血样胸痛，心电图表现出ST段改变、T波倒置，心肌酶等标志物水平轻度升高，是一过性的心尖部及心室中部局部室壁运动不良，但冠脉造影结果未见明显异常，大多预后良好，需与急性冠脉综合征相鉴别。但其具体发生机制，目前尚未明确。Tako-tsubo综合征的研究已引起人们的广泛关注，本文就其主要表现及发生机制方面的研究进展进行综述。The tako - tsubo syndrome, or transient left ventricular apical ballooning syndrome, first described by Japanese physicians, is more and more frequently described. This syndrome occurs mainly in women older than 60 years and it is frequently preceded by a physical or emotional stress. The clinical presentation looks like an acute coronary syndrome, with chest pain, electro cardiographic changes of ST - segment elevation or T wave inversion, and moderate cardiac enzymes release. Coronary angiography shows no significant coronary disease and ventriculography a systolic dysfunction with akinesia of mid- die and apical segments, leading apical ballooning, and basale hyperkinesia. These abnormalities are transient, with quick favorable outcome. The mechanism of the tako - tsubo syndrome is remains unknown. This paper described the characteristic and the mechanism of this syndrome.

关 键 词：应激或情感压力 可逆性左室功能紊乱 颅脑损伤 儿茶酚胺 

分 类 号：R541[医药卫生—心血管疾病]