普拉洛芬滴眼剂应用于激光虹膜切开术的临床观察  

Clinical study of the effectiveness of topical pranoprofen after laser iridotomy

作　　者：方敏[1] 包志淑[2] 张金顺[2] 

机构地区：[1]温州市第三人民医院,浙江温州32500 [2]温州医学院附属眼视光医院,浙江温州325027

出　　处：《中国医院药学杂志》2009年第11期920-920,921-922,共3页Chinese Journal of Hospital Pharmacy

摘　　要：目的:评估普拉洛芬滴眼剂在减轻激光虹膜切开术(LPI)术后炎症反应中的疗效及其不良反应。方法:80例(80眼)临床前期或早期闭角型青光眼患者行LPI,术后随机分为治疗组和对照组,试验组40例(40眼),选用0.1%普南扑灵滴眼剂点眼,对照组40例(40眼),选用0.1%氟米龙滴眼剂点眼。观察指标为眼部畏光、异物感、流泪、疼痛、眼肿等症状及充血、角膜上皮完整性、前房闪辉、前房浮游体等体征,以各项指标的综合评分评价其疗效。结果:治疗组在术后第1,3,7天综合评分与对照组比较,差异无显著性(P>0.05)。结论:普拉洛芬滴眼剂点眼能显著地减轻激光虹膜切开术术后的炎症反应。OBJECTIVE To evaluate the efficacy and safety of pranoprofen eye drops in relieving reactions of postoperative inflammation of laser iridotomy. METHODS A randomized and controlled study was adopted. 0. 1 % pranoprofen eye drops and 0. 1% fluorometholone eye drops, four times each day, were administered in treat and control group respectively. All pa tients have been observed for 7 days. Ocular pain, photophobia, epiphora, conjunctival congestion, aqueousflare, keratitis, iri disposterior was observed and recorded to calculate a comprehensive score. RESULTS There was no significant difference between the two groups at 1, 3, 7 days postoperatively. CONCLUSION 0. 1% Pranoprofen eye drops has excellent efficacy and safety to control the inflammation after laser iridotomy.

关 键 词：普拉洛芬滴眼剂 激光虹膜切开术 炎症反应 

分 类 号：R969[医药卫生—药理学]