男女性不育症8331例血清抗精子抗体检测结果分析  

Analysis of level of serum antisperm antibody in infertility patients

作　　者：季明勇[1] 黄明孔[1] 马天根[1] 郭健[1] 唐永军[1] 俞旭君[1] 

机构地区：[1]成都中医药大学附属第四医院,四川生殖卫生学院附属医院,成都610041

出　　处：《中国男科学杂志》2009年第5期46-48,共3页Chinese Journal of Andrology

摘　　要：目的观察男性和女性血清抗精子抗体的阳性率、滴度及其差异性。方法样本获自男科和妇科就诊的不育患者,血清分离后用精子浅盘凝集试验(TAT)和精子制动试验(SIT)检测,并用已知阳性和阴性血清作质控对照。结果男女性不育症8331例中,抗精子抗体阳性率26.8%,其中男性25.2%,女性29.9%,其差异有统计学意义(x^2=20.13,P<0.005)。抗精子抗体阳性的2 232例中,单一TAT阳性90.4%,TAT和SIT均阳性9.6%,无单独SIT阳性检出。TAT阳性率,男性不育症为25.2%,女性不育症为29.9%,其差异有统计学意义(x^2=26.29,P<0.001)。SIT阳性率,男性不育症为3.3%,女性不育症为1.3%,其差异有统计学意义(P<0.001)。结论免疫性不育在不育症诊疗中占有非常重要的地位。Objective To analyze the level of antisperm antibody（AsAb） in serum of Infertility Patients. Methods The level of antisperm antibody in serum of Infertility Patients were detected by TAT and SIT with a positive control and a negative control. Results In 8331 cases, the positive rate of AsAb was 26.8% and there was a significant difference in the positive rate of AsAb between male（25.2%） and female（29.9%）. In all patients with AsAb（＋）, the rate of only TAT（＋） was 90.4% and the rate of TAT（＋） and SIT（＋） was 9.6%. It couldn＇ t be found that only SIT（＋） was positive. The rate of TAT（＋） in male was 25.2% and in female was 29.9%, which showed the difference was significant. The rate of SIT（＋） in male was 3.3% and in female was 1.3%, which showed a significant difference. Conclusion Immune infertility should be attracted much attentions in the diagnosis and treatment of infertility.

关 键 词：抗精子抗体 不育 

分 类 号：R698.2[医药卫生—泌尿科学]