中医类核心杂志随机对照临床试验疾病谱的变化和趋势  

Change and Trend of Disease Spectrum in Randomized Controlled Trials of Traditional Chinese Medicine

作　　者：钟云青[1] 周维[1] 张绍英[2] 毛兵[1] 樊涛[1] 李文[1] 

机构地区：[1]四川大学华西医院中西医结合科,四川成都610041 [2]成都市第五人民医院,四川成都611130

出　　处：《四川中医》2009年第6期62-65,共4页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的：调查中医药治疗疾病谱的变化及其优势。方法：手工检索中医类13种核心期刊在1999～2007年发表的随机对照试验（randomized controlled trials，RCTs），建立RCrs数据库；对所研究疾病进行系统归类，同时对常见疾病进行分析，并与1980～1998年的RCTs数据库进行疾病谱的比较。结果：本数据库共计13909篇RCTs文献，以消化、心血管、神经、呼吸和妇科系统疾病文献最多。常见病以脑血管意外、糖尿病、冠心病、慢性阻塞性肺疾病和慢性肝炎的研究居多。与既往比较，神经、内分泌代谢、肿瘤和妇科疾病的系统构成比均有较大幅度的上升，而消化和呼吸系统的构成比均有较大幅度的下降。同时常见疾病脑血管意外由第5位升至第1住，糖尿病由第3位升至第2位，颈椎病则进入前10位疾病之列；冠心病由第1位降至第3位，慢性肝炎由第2位降至第5位。结论：中医工作者比较关注中医药在防治心脑血管、内分泌代谢、恶性肿瘤、老年和慢性疾病等方面的临床研究，中医药具有治慢病、治未病、注重整体性、经济性和毒副反应少等优势。Objective： To investigate the spectrum changes of diseases with the treatment of Traditional Chinese Medicine （TCM）, and to investigate the advantage of TCM.Methods： A manualsearch for papers of randomized controlled trials was performed in 13 core periodicals of TCM publlshed from 1999 to 2007, and a database about RCTs was estabfished.Aecording to the established database, diseases were sorted systematically.Among them, the common diseases were analyzed, and the disease spectrum was compared with that gotten from the RCTs database founded from 1980 to 1998.Resuhs： Total 13909 RCTs were identified in the database, which respiratory system, and gynecological system.Cerebrovasclar accident, diabetes mellitus, coronary heart disease, chronic obstructive pulmonary disease and chronic hepatitis are in the majority of research on diseases. As compared with the previous materials, the constituent ratios of nervous system disease, endocrine metabolic disease, tumor, gynecology disease from 1999 to 2007 were raised, while those of digestive and respiratory system disease were lowered. Meanwhile in the common diseases, cerebrovasctdar accident in constituent ratios elevated rom the 5th to 1st, diabetes mellitus from 3rd to 2nd, and cervical spondylosis entry into first ten, while coronary heart disease declined from the 1st to the 3rd, chronic hepatitis from 2nd to 5th.Conclusions： Researchers of TCM often focus on the clinical study about the application of Traditional Chinese Medicine in prevention and treatment on cardio-cerebrovascular disease, endocrine metabolic disease, malignant tumor, geriatric and chronic diseases, and TCM possess of the superiority in treating chronic diseases, preventing from diseases, emphasizing entirety, saving economy, and low adverse reaction.

关 键 词：中医 随机对照试验 疾病谱 

分 类 号：R195.4[医药卫生—卫生统计学]