磷脂DHPC和短杆菌肽D相互作用的DSC研究  

DSC Study of the Interactions of Phospholipid DHPC and Gramicidin D

作　　者：王邦宁[1] 谈夫[1] 

机构地区：[1]中国科学院化学研究所,北京100080

出　　处：《物理化学学报》1998年第6期548-551,共4页Acta Physico-Chimica Sinica

基　　金：国家自然科学基金

摘　　要：Changes of the behavior of the thermotropic phase transitions of the phospholipid DHPC by the action of miniprotein gramicidin D (G.D) have been studied by differential scanning calorimetry. The experimental results demonstrated that G.D could not remove the pretransition of DHPC, but the pretransition peak and the main transition peak of DHPC were incorporated into a broad peak. The pretransition temperature and the main transition temperature of DHPC decreased to different ex-tent. The sums of the pretransition and main transition enthalpies of DHPC showed a lineally decreasing relationship with increasing the mole fraction x_g of gramicidin D.Changes of the behavior of the thermotropic phase transitions of the phospholipid DHPC by the action of miniprotein gramicidin D (G.D) have been studied by differential scanning calorimetry. The experimental results demonstrated that G.D could not remove the pretransition of DHPC, but the pretransition peak and the main transition peak of DHPC were incorporated into a broad peak. The pretransition temperature and the main transition temperature of DHPC decreased to different ex-tent. The sums of the pretransition and main transition enthalpies of DHPC showed a lineally decreasing relationship with increasing the mole fraction x_g of gramicidin D.

关 键 词：生物膜 磷脂 GD DSC DHPC 相互作用 短杆菌肽 

分 类 号：Q545.02[生物学—生物化学] Q514.302