生物合理设计光系统Ⅱ抑制剂研究(Ⅱ)3-苯甲氨基-2-氰基-3-甲硫基丙烯酸乙酯的晶体及分子结构  

Studies on Bio rational Design of Photosystem Ⅱ Inhibitors(Ⅱ) The Crystal and Molecular Structure of Ethyl 3-Benzylamino-2-cyano-3-methylthioacrylate

作　　者：刘华银[1] 扬光富 陆荣健[1] 谭惠芬[1] 杨华铮[1] 来鲁华[2] LIU Hua-Yin;YANG Guang-Fu;LU Rong-Jian;TAN Hui-Fen;YANG Hua-Zheng;LAI Lu-Hua(The Institute of Elemento Organic Chemistry,National Elemento Organic Chemistry Key Laboratory,Nankai University,Tianjin,300071;The Institute of Physical Chemistry,Peking University,Beijing 1008711)

机构地区：[1]南开大学元素有机化学研究所,元素有机化学国家重点实验室,天津300071 [2]北京大学物理化学研究所,北京,100871

出　　处：《高等学校化学学报》1998年第6期899-902,共4页Chemical Journal of Chinese Universities

基　　金：国家自然科学青年基金;天津市自然科学基金

摘　　要：合成了具有良好光合作用抑制活性的标题化合物,测定了其晶体结构.确定了该类化合物的顺反构型,阐明了苯环与氨基间亚甲基对化合物抑制活性的重要作用,解释了氨基氢与酯羰基氧间没有形成氢键的原因.Based on the structure of D1 protein of photosystem Ⅱ of Pisum sativum , the title compound with good Hill reaction inhibition was designed and synthesized, and its structure was confirmed by X ray diffraction. It was found that the CH 2 group between phenyl and amino is important for compounds inhibition, and there is no H binding in the molecule.

关 键 词：PSⅡ抑制剂 光合作用抑制剂 丙烯酸酯衍生物 

分 类 号：TQ457.2[化学工程—农药化工]