铱(Ⅰ)联萘胺Schiff碱(BPMBNDI)配合物催化苯乙酮的不对称氢转移反应  

Asymmetric Transfer Hydrogenation of Acetophenone Catalyzed by Iridium(I) Complexes with BPMBNDI

作　　者：自国甫 尹承烈[1] 

机构地区：[1]北京师范大学化学系,北京100875

出　　处：《化学学报》1998年第5期484-488,共5页Acta Chimica Sinica

基　　金：国家自然科学基金(29372038);国家教委博士点基金资助项目

摘　　要：用旋光活性2,2′-(1,1′-联萘)二胺和2-吡啶基甲醛缩合得到的Schiff碱BPMBNDI[N,N′-二(2-吡啶基亚甲基)-(1,1′-联萘)-2,2′-二亚胺]为配体与[Ir(COD)Cl]_2(COD=1,5-环辛二烯)反应,生成了10个光学活性铱配合物.研究它们在异丙醇对苯乙酮不对称氢转移反应中的光学诱导活性时,发现10个催化剂均具有较高的立体选择性,其中[Ir(COD)(BPMBNDI)I]催化的光学产率高达84%.Ten chiral iridium complexes were synthesized from (R) - ( + ) or (S)-(-)-2,2' - diamino- 1,1' - binaphthyl(DABN) and [Ir(COD)Cl]2 (COD =1,5- cyclooctadiene). The complexes were used as enantioselective catalysts in the asymmetric hydrogen transfer reactions of acetophenone. All the catalysts have high activity and selectivity and the highest optical yield was up to 84%.

关 键 词：铱 配合物 席夫碱 不对称 氢转移 苯乙酮 催化剂 

分 类 号：O625.42[理学—有机化学] O643.36[理学—化学]