边防军人116例低血压患者内皮源性心血管活性物质及血管加压素测定结果分析  

Laboratory Detection Result Analysis of Endothelium-derived Cardiovascular Active Material and Vasopressin of 116 Cases of Hypotension Patients of Frontier-defense Servicemen

作　　者：薛越 刘长林 金兆清 

机构地区：[1]解放军第16医院,新疆阿勒泰836500

出　　处：《临床军医杂志》2009年第3期398-399,共2页Clinical Journal of Medical Officers

基　　金：兰州军区医药卫生科研基金资助项目(NO:LXH-2007028)

摘　　要：目的探讨新疆北部边防军人低血压与内皮源性心血管活性物质[内皮素Ⅰ(ET-Ⅰ)、血管紧张素Ⅱ(ANG-Ⅱ)、一氧化氮(NO)]及血管加压素(ADH)的关系。方法采用普查的方法在1664例官兵中筛选出低血压患者116例为低血压组,用ELLSA法测定血清中ET-Ⅰ、ANG-Ⅱ、NO、ADH含量。然后与随机抽取100例血压正常的官兵(对照组)血清中上述物质含量进行比较。结果低血压组NO显著高于对照组(P<0.01);ET-Ⅰ、ANG-Ⅱ、ADH低血压组显著低于对照组(P<0.01)。结论低血压的发生是ET-Ⅰ、ANG-Ⅱ、ADH、NO这几种血管活性物质及其他物质综合作用的结果。Objective To explore the relationship between ET-I ,ANG-Ⅱ,NO,ADH and hypotension of frontier-defenee servicemen in northern part of XinJiang. Methods 116 cases of hypotension patient （ hypotension group） were selected through general investigation from 1664 soldiers, the contents of ET-I、ANG-Ⅱ,NO,ADH in their serum was tested by ELLSA, then, the results were compared with 100 soldiers （control group） whose blood pressure are normal and were selected at random. Results NO in hypotension group is significant higher than control group（P〈0.01） , all of ET-I、ANG-Ⅱ、ADH are significant lower than control group （ P 〈0.01）. Conclusion Hypotension in frontier-defence troops is the results of synthetic action of ET-I、ANG-Ⅱ, ADH、NO and others materials.

关 键 词：低血压 内皮素Ⅰ 血管紧张素Ⅱ 一氧化氮 血管加压素 

分 类 号：R544.2[医药卫生—心血管疾病]