抗感染活性骨与自体骨在骨不连治疗中的对比研究  

Comparative Study of Anti-infective Reconstituted Bone Xenograft with Autogenous Hone in Patients with Bone Non-union

作　　者：刘建敏[1] 袁志[1] 刘建[1] 胡蕴玉[1] 穆尚强[1] 卫磊[1] 李丹[1] 

机构地区：[1]第四军医大学西京医院全军骨科研究所,陕西省西安市710032

出　　处：《中国骨与关节损伤杂志》2009年第6期507-508,共2页Chinese Journal of Bone and Joint Injury

基　　金：国家科技支撑计划课题(2006BAI16B02);"九五";"十五";"十一五"全军医药卫生科研基金指令或重大课题(96L052);(01Z079);(06Z057)

摘　　要：目的对比研究抗感染活性骨(ARBX)与自体骨治疗四肢长骨非感染性骨不连的疗效。方法通过病例回顾研究,比较ARBX与自体髂骨植骨治疗非感染性骨不连的疗效。结果两组随访95例,随访时间平均4年6个月。ARBX植骨29例,其中26例完全愈合,3例未愈合,骨性愈合率为89.7%;自体髂骨植骨66例,其中60例完全愈合,6例未愈合,骨性愈合率为90.9%。结论ARBX植骨与自体髂骨植骨治疗四肢非感染性骨不连的疗效相当;ARBX具有良好的骨传导、骨诱导作用,是一种良好的植骨材料。Objective To compare curative effects of anti-infective reconstituted bone xenograft with autogenous bone in patients with non-infective non-union of long bone of limbs. Methods The curative effects of anti-infective reconstituted bone xenograft and autoge- nous bone in patients with non-infective non-union were compared by retrospective study of cases. Results In the total followed up pa- tients, 95 cases were followed up for more than 12 months and the average time was 4 years and 6 months （ranging from 1 year to 6 years and 8 months）. In the 29 cases who were treated with ARBX bone grafted, 26 cases had complete bone union, but the other 3 cases still had bone nonunion. The cure rate was 89.7%. In the 66 cases who received autogenous bone grafted, 60 eases had complete bone union, 6 cases remained nonunion. The cure rate was 90.9%. Conclusion The overall curative effects ware similar in patients of the two groups. ARBX have the good capacity of bone conduction and bone induction, and it is a favorable bone graft material.

关 键 词：骨不连 植骨 自体骨 异种骨 

分 类 号：R683[医药卫生—骨科学] R683.41[医药卫生—外科学]