益气养阴法对冠心病患者内皮素及生活质量的作用研究  

Clinical Observation of Yiqi Yangyin Methods on Endothelin and Quality of Life in Patients with Coronary Heart Disease

作　　者：顾颖敏[1] 叶穗林[1] 黄洁红[1] 何皓颋[1] 高雅琦[1] 

机构地区：[1]广州市中医医院,广东广州510130

出　　处：《辽宁中医杂志》2009年第6期939-940,共2页Liaoning Journal of Traditional Chinese Medicine

摘　　要：目的:研究益气养阴法对冠心病患者内皮素及生活质量的作用。方法:100例冠心病患者随机进入治疗组和对照组各50例,对照组予以基础治疗上服用单硝酸异山梨酯片,治疗组在基础治疗上加用生脉散,4周为1个疗程,持续3个疗程;观察治疗前后症状和体征、临床疗效、血浆内皮素浓度(Endothelin,ET)以及生活质量的情况。结果:治疗后,治疗组对冠心病患者的临床症状、血浆内皮素浓度及生活质量的作用,均优于对照组,除临床疗效外,差异具有统计学意义(P<0.01)。结论:生脉散对改善冠心病患者的内皮素水平和生活质量具有确切的疗效。Objective： To observe the effect of Yiqi Yangyin methods on Endothelin and Quality of Life in patients with coronary heart disease. Methods：100 patients with coronary heart disease were randomly divided into two groups. Patients in control group（ n = 50）were treated by Isosorbide Mononitrate tablets and routine therapy. Patients in treatment group（ n = 50）were treated by combination of Shengmaisan and routine therapy , with a treatment course of 12 weeks. Clinical symptoms, clinical effect , Endothelin and quality of life were observed before and after treatment. Results ： Clinical symptoms, Endothelin and quality of life in treatment group were superior to control group after treatment （ P 〈 0. 05 ）, there was a significant difference between the two groups except clinical effect（ P 〈 0.01 ）. Conclusion：Shengmaisan is effective in improving Endothelin level and quality of life.

关 键 词：冠心病 益气养阴法 内皮素 生活质量 生脉散 

分 类 号：R541.4[医药卫生—心血管疾病]