不孕奶牛用复方缩宫素乳剂处理后外周血中雌二醇和孕酮水平的变化  

Estradiol and progesterone levels in sera of infertile dairy cows after treatment with Oxytocin Compound Emulsion

作　　者：杨利国[1] 刘荣军[1] 王元兴[1] 

机构地区：[1]南京农业大学动物科技学院

出　　处：《南京农业大学学报》1998年第2期73-76,共4页Journal of Nanjing Agricultural University

基　　金：江苏省科委九五重点科技攻关项目

摘　　要：选择患持久黄体、卵巢静止和慢性子宫内膜炎的奶牛各１０头，从每种疾病类型中各选半数牛于宫内灌注复方缩宫素乳剂，其余患牛用生理盐水处理作为对照。各组患牛于处理当天和处理后第１，３，５，７，１０，１４和２１ｄ采血，用放射免疫测定方法分析血中１７β－雌二醇（Ｅ２）和孕酮（Ｐ４）水平。结果发现，持久黄体患牛在处理后血中Ｅ２水平不断升高，Ｐ４水平逐渐降低；卵巢静止患牛在处理后血中Ｅ２和Ｐ４水平均升高；慢性子宫内膜炎患牛在处理前血中Ｅ２和Ｐ４水平介于前两种病牛之间，处理后血中Ｅ２水平逐渐升高，Ｐ４水平逐渐降低。这些结果证明。Infertility of persistent corpus luteum (PCL), inactive ovaries (AAO) or endometritis (EDM) were studied. Ten cows were used in each kind of infertility, in which 5 cows were treated with Oxytocin Compound Emulsion (OCE), another 5 cows were treated with normal saline as controls. Blood sera were collected from all cows on day of treatment and days 1, 3, 5, 7, 10, 14 and 21 posttreatment. The levels of 17βestradiol and progesterone in sera were detected by radioimmunoassay. The results indicated that estradiol concentration increased but progesterone level decreased gradually in cows with PCL after OCE treatment. The concentrations of both estradiol and progesterone in cows with AAO increased after the treatment. Cows with EDM had higher levels than cows with AAO and lower hormone levels than cows with PCL on the day of pretreatment. The estradiol increased but progesterone decreased after the treatment. These results suggested that OCE was able to induce luteolysis and estrus in infertile cows.

关 键 词：不孕症 治疗 雌二醇 孕酮 牛病 乳牛 

分 类 号：S858.237.2[农业科学—临床兽医学]