细茎银莲花的化学成分  

Chemical constituens of Anemone rossii Moore

作　　者：路金才[1] 张娜[1] 单娜[1] 贾丽丽[1] 樊莉[1] 

机构地区：[1]沈阳药科大学中药学院,辽宁沈阳110016

出　　处：《中国药物化学杂志》2009年第3期209-211,共3页Chinese Journal of Medicinal Chemistry

摘　　要：目的对细茎银莲花(Anemone rossii Moore)根茎的化学成分进行初步研究。方法细茎银莲花根茎以体积分数为75%的乙醇提取,提取物经系统溶剂萃取,对其氯仿萃取部分进行反复柱色谱分离,利用理化性质和波谱分析进行结构鉴定。结果从细茎银莲花根茎中分离得到7个已知化合物,分别为桦皮醇(1)、桦皮酸(2)、齐墩果酸(3)、β-谷甾醇(4)、香豆素(5)、4,7-二甲氧基-5-甲基香豆素(6)、齐墩果酸-3-O-α-L-吡喃阿拉伯糖苷(7)。结论所有化合物均为首次从细茎银莲花中分离得到。Aim To study the chemical constitutents from rhizome of Anemone rossii. Methods The rhizome of the plant were extracted with 75% ethanol, the ethanol extract was extracted then with petroleum ether, chloroform, ethyl acetate and n-butanol respectively. The chloroform extraction was submitted to chromatography on silica gel column and seven compounds were isolated. Their structures were elucidated on the basis of physical-chemical method, spectral analysis and by comparison with certain authentic samples. Results The isolated compounds were identified as betulin （ 1 ）, betulic acid（2 ）, oleanolic acid （ 3 ） ,β-sitosterol （ 4 ）, coumarin（5 ）, 4,7-dimethoxyl-5-methyl-coumafin （ 6 ）, and oleanolic acid-3-O-α-L-arabinopyranoside （ 7 ）. Conclusion All these compounds are isolated from Anemone rossii Moore for the first time.

关 键 词：细茎银莲花 化学成分 结构鉴定 色谱法 

分 类 号：R284.1[医药卫生—中药学]