彩色和频谱多普勒超声肾血流分析对于糖尿病肾病的临床价值  

EVALUATION OF COLOR DOPPLER FLOW IMAGEIN PATIENTS WITH DIABETIC NEPHROPATHY

作　　者：胡肇衡[1] 毛腾淑[1] 李正荣[1] 毛迅 张颖[1] 

机构地区：[1]北京医科大学人民医院内分泌科

出　　处：《北京医科大学学报》1998年第3期227-229,共3页Journal of Peking University(Health Sciences)

摘　　要：目的：探讨彩色和频谱超声多普勒肾血流分析对糖尿病肾病的临床价值。方法：２５７例糖尿病患者按Ｍｏｇｅｎｓｅｎ方法分为５组，分析肾血管阻力指数（ＲＩ）和搏动指数（ＰＩ）。结果：糖尿病肾病除高滤过组ＲＩ（０．６４）低于对照组ＲＩ（０．６７）外（Ｐ＜０．０５），各组随病程的进展ＲＩ逐步升高。ＲＩ≥０．８０主要分布在临床糖尿病肾病和氮质血症期组（９６．９％）。ＲＩ与肾小球滤过率（ＧＦＲ）显著负相关。结论：彩色和频谱超声多普勒肾血流分析对判断糖尿病肾病早期的改变和对晚期病变的预示有一定的临床价值。Objective: To determine the renal Doppler ultrasonography (US) findings in diabetic nephropathy. Methods: 257 patients with diabetic mellitus that were divided into 5 groups according to method of Mogensen and described underwent renal color Doppler [resistive index (RI) measurement] US examination. Results: The renal mean RI's in each group were gradually increased with the stages advanced of diabetic nephropathy (DN) except the mean RI was significantly lower than that of normal subjects in group 1 (early hypertrophyhyperfunction). The patients of RI≥0.80 were distributed in group 4 (overt DN) and group 5 (endstage renal failure due to DN) (96.9%). The RI was negatively correlated to GFR. Conclusion: Renal Color Doppler US is a helpful noninvasive tool in detecting early hypertrophyhyperfunction stage of renal function and providing information for the prognosis of DN in diabetic patients.

关 键 词：糖尿病 肾病 病理生理学 肾血流量 多普勒超声 

分 类 号：R587.2[医药卫生—内分泌] R692.04[医药卫生—内科学]