益心脉颗粒对慢性心力衰竭患者心功能及AngⅡ影响的研究  

The effect of Yi Xin Mai Granule on the heart function and the changes of plasma levels of Ang H in chronic systolic heart failure patients

作　　者：唐建红[1] 刘川玉[1] 符显昭[1] 苏涵[1] 

机构地区：[1]桂林医学院附属医院,541001

出　　处：《中国临床实用医学》2009年第6期35-37,共3页China Clinical Practical Medicine

摘　　要：目的评价益心脉颗粒对慢性心力衰竭（Chronic heart failure，CHF）患者的疗效及血浆血管紧张素Ⅱ（angiotrnsionⅡ，AngⅡ）的含量变化的影响。方法将CHF患者设为对照组和治疗组，分别进行西药常规治疗和加服益心脉颗粒治疗，检测CHF患者治疗前后AngⅡ的血浆含量变化，同时选10例健康体检者作为正常对照组。结果治疗组AngU含量较对照组降低更为显著（P〈0．01），治疗组总有效率93．33％，西药常规治疗组总有效率80．00％，两组疗效比较P〈0．05，两组LVEF值提高，A／E值下降，但以治疗组变化明显（P〈0．01）。结论益心脉颗粒与西药常规治疗配合使用，疗效优于单用西药治疗。Objective To investigate the curative effects of Yi Xin Mai Granule on chronic systolic heart failure patients and the influence on the changes of plasma levels of angiotrnsion U（ Ang Ⅱ）. Methods CHF were divided into control group and treatment group, The control group were treated with traditional com- prehensive therapy of west medicine, YXMG was added in treatment group. The changes of the levels of Ang Ⅱ. 10 Healthy subjects served as normal group. Results Ang Ⅱ ＇ s Levels of Plasma of tow group decreased re- markably after treatment（P 〈0. 01 ） ,The total effective rate of treatment group was 93.33% ,and control group only 80. 00% （P 〈0. 005 ）. After treatment,the LVEF in tow group patients increased and the A/E decreased, but the changes in Treatment group was obvious （ P 〈 0. 01 ）. The effects of treatment group are better than that of the control group. Conclusion The effects of Treatment group are better than that of control group.

关 键 词：心力衰竭 血管紧张素Ⅱ 益心脉颗粒 中西医结合 

分 类 号：R541.6[医药卫生—心血管疾病]