药物导入对关节影响的组织学观察  

The Morphologic Study of the Effect of Chinese Herb Iontophoresis on Joint

作　　者：徐晓东[1] 

机构地区：[1]山东省临沂市人民医院骨科,276000

出　　处：《中国临床实用医学》2009年第6期45-46,共2页China Clinical Practical Medicine

摘　　要：目的通过中药电导入与电刺激对比研究，探讨中药电导入对关节影响的作用原理，并比较差异。方法中药制剂直流电导入兔髋关节，用同频率、同强度直流电组、空白组对照。通过形态学观察，有关指标测定，了解关节囊、软骨的改变。结果中药电导入组和电刺激组关节囊血管直径增大，密度增加。细胞器功能活跃。软骨细胞密度增加，细胞器功能活跃。测量毛细血管密度、管腔直径，软骨细胞密度，前两组高于后组P〈0．01。中药电导入组、电刺激组之间有显著性差异P〈0．05，前者高于后者。结论中药电导入有电刺激和中药双重作用，促进细胞增生和细胞器功能，组织修复能力加强，改善骨关节炎症状。Objective To find out the working principle of Chinese herb on degenerative disease of joint by contrast it with single electrical stimulation. Methods 18 healthy rabbits were randomly divided into 3 groups, A, B, C,. The water-boiled dose of Chinese herb was iontophored into the hip joint of group A. Group B received single pulsive electrical stimulation with the same frequency and density. Group C was controll group without any treatment. The means of morphologic observing was used to investigate the adaptive changes of the capsule and cartilage. Results Chinese herb iontophoresis raised the blood supply of the tissue of capsule sig, nificantly and improved the function of cell organ of the tissues in comparison with the controll group. Conclu- sion Chinese herb iontophoresis had the effect of both electrical stimulation and herb, it can enhance the func- tion of cell organ and blood supply of the tissues, the ability to repair strengthened. Chinese herb iontophoresis was beneficial for orthopaedic degenerative disease without hurt to tissue.

关 键 词：药物导入 组织学 临床研究 治疗方法 

分 类 号：R28[医药卫生—中药学]