肱骨近端骨密度的测量及其与年龄和体质量指数的相关性研究  

Measurement of bone mineral density in the proximal humeral region

作　　者：朱前拯[1] 付中国[1] 张殿英[1] 姜保国[1] 

机构地区：[1]北京大学人民医院创伤骨科,北京大学交通医学中心,100044

出　　处：《中华创伤骨科杂志》2009年第6期523-526,共4页Chinese Journal of Orthopaedic Trauma

基　　金：基金项目：国家“十一五”科技支撑计划基金（2007BA104806）

摘　　要：目的建立一种肱骨近端骨密度（BMD）的测量方法，研究肱骨近端BMD与年龄和体质量指数（BMI）的关系，探讨肱骨近端BMD在预报骨质疏松症的敏感性。方法选择绝经后健康女性志愿者，使用HologicDELPHI—A双能X射线骨密度仪及本研究设计的肩部定位器和前臂定位器测量肱骨近端BMD。研究第一部分包括30名志愿者，每人连续测量右侧肱骨近端BMD2次，根据测量结果计算短期精密度RMSSD和RMSCV；第二部分包括92名志愿者，记录其年龄、身高、体重，测量右侧肱骨近端BMD，分析肱骨近端BMD与年龄和BMI的相关性。结果本研究肱骨近端BMD测量方法的短期精密度：RMSSD=0．011g／cm2，RMSCV=2．4％。本研究92名志愿者平均（60．2±6．4）岁，平均身高（159．5±5．4）cm，平均体质量（59．4±7．5）kg，平均BMI23．3±2．7，平均肱骨近端BMD（0．543±0．083）g／cm2，肱骨近端BMD同年龄呈负相关，同BMI无显著相关。结论本研究建立了一种测量肱骨近端BMD的方法；年龄越大肱骨近端BMD越低；由于BMI对BMD的影响会掩盖骨质的丢失，而非负重区域即肱骨近端会最大程度地减少BMI对BMD的影响程度。Objective To establish a method of measuring bone mineral density （BMD） in the proximal humeral region, and explore the relationship between proximal humeral BMD level and age and body mass index （BMI）. Methods A scanning procedure was developed, using a shoulder ＆ forearm position device. Firstly, 30 subjects were examined on the proximal humerus with 2 successive scan sessions to determine the short-term precision. Secondly, scanning of the right proximal humerus BMD in 92 healthy women was done. Results Short term precision revealed that RMS SD was 0. 011 g/cm2, and RMS CV （coefficient of variation） on BMD measurement was 2.4%. Proximal humeral BMD values decreased with age. No correlation existed between the proximal humeral BMD and BMI. Conclusions The method of measuring BMD over the proximal humeral region is reasonable, and the short term precision of the result is acceptable. Proximal humeral BMD tends to decrease with age. Since the shoulder is subject to the least influence of weight and stress loading, the proximal humeral BMD scan might be an early stage indicator of osteoporosis.

关 键 词：肱骨 骨密度 骨质疏松 年龄相关 骨折 

分 类 号：R686[医药卫生—骨科学]