抗磷脂综合征患者妊娠结局分析  

Nursing intervention of pregnant women with antiphosphofipid syndrome

作　　者：阳伟华[1] 彭可[1] 方芙蓉[1] 

机构地区：[1]惠州中心医院妇产科,广东省惠州516001

出　　处：《中国基层医药》2009年第5期798-799,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨妊娠并抗磷脂综合征患者的妊娠结局及相关护理。方法，选择抗心磷脂抗体（ACA）阳性孕妇40例作为观察组和40例ACA阴性的孕妇为对照组，比较两组患者的妊娠结局情况。结果观察组发生流产6例（15．0％），死胎2例（5．0％），妊娠丢失8例（20．0％）；对照组发生流产2例（5．0％），无死胎，妊娠丢失2例（5．0％）；观察组妊娠丢率失明显高于对照组（χ^2=9．54，P〈0．05）；采用相应治疗护理后（孕中期）ACA—Igg阳性率达40．0％低于治疗前的52．5％（χ^2=3．85，P〈0．05）；产后1月ACA—IgM阳性率37．5％低于孕中期40．0％（χ^2=3．81，P〈0．05）。结论ACA阳性与妊娠丢失有密切的关系，采取相应的治疗护理干预可提高疗效，减少妊娠并发症。Objective To investigate the nursing intervention of pregnant women with antiphospholipid syndrome（APS）. Methods In experimental group 40 eases with APS positive and control group 40 cases with APS ACA-negative for comparison. Results The abortion oeeured in 6 eases（ 15.0% ） ,2 eases of stillbirth（5.0% ） ,loss of pregnancy （ abortion ＋ stillbirth ） 8 cases （ 20. 0% ） in experimental group. The abortion occurred in 2 eases （5.0%） ,no stillbirth in control group. The loss of pregnancy in experimental group were significantly higher than the control group（ χ^2 =9.54,P 〈 0. 005 ）. The rate of positive in ACA-IgG（40. 0% ） after treatment lower than before treatment （ 52. 5 % ） （ χ^2 = 3.85, P 〈 0. 05 ）. The rate of positive in ACA IgM （37.5 % ） after treatment lower than be- fore treatment （ 40. 0） % （χ^2 = 3, 81, P 〈 0.05 ）. Conclusion The APS positive rate and the loss of pregnancy were closely related. The overall nursing intervention conld improve efficacy and reduce the complications.

关 键 词：抗磷脂综合征 妊娠 护理干预 

分 类 号：R473[医药卫生—护理学]