超声造影在乳腺局灶性病变中的应用  

Application of contrast-enhanced ultrasound in the diagnosis of breast lesions

作　　者：陈利民[1] 贺军[1] 柳刚[1] 李跃丰[1] 王红华[1] 李蓓蕾[1] 

机构地区：[1]温州市第二人民医院超声科,浙江温州325000

出　　处：《全科医学临床与教育》2009年第3期232-234,F0003,共4页Clinical Education of General Practice

基　　金：温州市科学技术委员会(Y2005B024)

摘　　要：目的探讨超声造影在乳腺肿块良、恶性病变鉴别诊断中的价值。方法应用超声造影观察48例女性乳腺肿块患者肿块内造影剂灌注特点及增强程度,并用时间-强度分析软件(ACQ)进行分析。结果良性肿块80.65%(25/31)表现为轻中度增强,ACQ曲线转折处多较圆钝,呈单向;恶性肿块88.24%(15/17)呈明显增强,ACQ曲线转折处多较锐利,呈多相。良性肿块达峰强度、增强强度、斜率低于恶性组(t=5.89、5.50、6.15,P均<0.05);达峰时间、增强时间、到达时间高于恶性组(t=4.62、9.14、2.18,P均<0.05)。结论超声造影提高了超声对乳腺良、恶性肿瘤的鉴别能力。Objective To investigate the value of contrast-enhanced ultrasonography in the diagnosis of breast lesions. Method Contrast-enhanced ultrasonography was performed on 48 patients with breast mass. The infusing characteristic of contrast agent and degree of contrast-enhanced were observed. The dynamic contrast-enhanced ultrasonography images were analyzed with the time-intensity curve software. Results 80.65%（25/31）of the benign mass was light to moderate enhancement and 88.24% （15/17）of the malignant mass was high enhancement. Turn in the curve of benign mass was blunt, but was sharp in the curve of malignant mass. The peak intensity, enhanced intensity and slope of the rising part were lower in the benign group than that in the malignant group （t = 5.89,5.50,6.15 ,P〈0.05）.The time to peak enhancement, enhanced time and arrived time were longer in the benign group than those in the malignant group （t=4.62,9.14,2.18,P〈0.05）. Conclusions Contrast-enhanced ultrasonography may improve the ability of ultrasound in the differentiation of benign and malignant breast masses.

关 键 词：声诺维 超声造影 乳腺肿块 

分 类 号：R445.1[医药卫生—影像医学与核医学] R735.704[医药卫生—诊断学]