社区获得性肺炎的病原体调查与药物敏感性分析  

Pathogenic study and sensitive antibiotics of community-acquired pneumonia

作　　者：陈光福[1,2] 胡元生 沈继龙[1,2] 石杜鹃[4] 刘丽丽[1,2] 李若梅 汪学龙[1,2] 温和 

机构地区：[1]教育部省部共建重要遗传病基因资源利用重点实验室 [2]安徽医科大学病原生物学教研室,安徽合肥230032 [3]安徽医科大学第三附属医院检验科,安徽合肥230061 [4]安徽医科大学第一附属医院检验科,安徽合肥230022

出　　处：《中华疾病控制杂志》2009年第3期273-276,共4页Chinese Journal of Disease Control & Prevention

基　　金：合肥市科技局重点项目(2005-08)

摘　　要：目的研究社区获得性肺炎CAP病原体种类、药物敏感性等,为临床有效诊断、治疗提供依据。方法对154名社区获得性肺炎患者的标本进行细菌培养和血清学检测,并进行药物敏感性试验。用PCR检测社区获得性肺炎非典型病原体。结果在社区获得性肺炎患者中多重感染十分常见;在典型病原体感染中,以肺炎链球菌最为常见;在非典型病原体感染中,以肺炎支原体最为常见,非典型病原体感染在8～14岁阶段检出率最高;明确了各种病原体对常用抗菌药物的敏感性。结论明确了该地区社区获得性肺炎的病原谱,及其对药物敏感性的差异,为临床有效治疗提供了依据。Objective To investigate the categories and sensitive antibiotics for pathogens from patients with community-acquired pneumonia（CAP） so as to orient clinical diagnosis and treatment. Methods Bacterial culture, serological detection and DNA amplification were carried out simultaneously for each sample of 154 patients. Pathogens resistance to frequently used antibiotics was tested. Results Multiple infections were common in CAP patients. Streptococcus pneumoniae was the most common organisms among typical pathogens infection. Mycoplasma pneumoniae was frequently noted in atypical pathogens infection. Atypical pathogens were mostly found in the individuals from 8 to 14 years old. The sensitive antibiotics for pathogens were identified. Conclusions Based on the test of drug resistance, the pathogens sensitive antibiotics should be used for treatment of CAP patients.

关 键 词：肺炎 社区获得性感染 病原 微生物敏感性试验 

分 类 号：R563.1[医药卫生—呼吸系统]